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月腺大戟的化学成分
引用本文:邓彬,穆淑珍,郝小江.月腺大戟的化学成分[J].中国天然药物,2010(3):183-185.
作者姓名:邓彬  穆淑珍  郝小江
作者单位:贵州省、中国科学院天然产物化学重点实验室;
基金项目:supported by the Science and Technology Projects of Guizhou Province,China(J[2008]2147)~~
摘    要:目的:研究月腺大戟(Euphorbia ebracteolata Hayata)植物根部中的化学成分。方法:采用各种色谱方法分离纯化化合物,并根据理化性质和波谱数据鉴定其结构。结果:分离得到8个化合物,分别被鉴定为:巨大戟二萜-3-肉豆蔻酸酯(1)、巨大戟二萜-3-棕榈酸酯(2)、9,19-环阿尔廷-23E-稀-3β,25-二醇(3)、24-亚甲基环阿尔廷烷-3,28-二醇(4)、β-香树酯醇乙酸酯(5)、狼毒乙素(6)、2,4-二羟基-6-甲氧基-3-醛基苯乙酮(7)和月腺大戟素A(8)。结论:化合物1~4均为首次从该植物中分离得到。

关 键 词:月腺大戟  化学成分  巨大戟烷型二萜

Chemical Constituents from Euphorbia ebracteolata
DENG Bin,MU Shu-Zhen,HAO Xiao-Jiang Key Laboratory of Chemistry for Natural Products of Guizhou Province , Chinese Academy of Sciences,Guiyang ,China.Chemical Constituents from Euphorbia ebracteolata[J].Chinese JOurnal of Natural Medicines,2010(3):183-185.
Authors:DENG Bin  MU Shu-Zhen  HAO Xiao-Jiang Key Laboratory of Chemistry for Natural Products of Guizhou Province  Chinese Academy of Sciences  Guiyang  China
Institution:DENG Bin,MU Shu-Zhen,HAO Xiao-Jiang* Key Laboratory of Chemistry for Natural Products of Guizhou Province , Chinese Academy of Sciences,Guiyang 550002,China
Abstract:AIM:To investigate the chemical constituents from the roots of Euphorbia ebracteolata Hayata.METHODS:Compounds were isolated and purified by various chromatographic methods.Their structures were identified by their physicochemical properties and spectroscopic data.RESULTS:Eight compounds were isolated and identified as ingenol-3-myristinate(1),ingenol-3-palmitate(2),9,19-cyclolanost-23E-ene-3β,25-diol(3),24-methyl-enecycloartane-3,28-diol(4),β-amyrin acetate(5),2,4-dihydroxy-6-methoxy-3-methyl-1-acetophenone(6),2,4-dihy-droxy-6-methoxy-3-formyl-1-acetophenone(7) and ebracteolatain A(8),respectively.CONCLUSION:Compounds 1-4 were isolated from the roots of the plant for the first time.
Keywords:Euphorbia ebracteolata Hayata  Chemical constituents  Ingenane type diterpenoids  
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