| 记忆性T细胞和HIV疫苗 |
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| 引用本文： | 王卫,魏强. 记忆性T细胞和HIV疫苗[J]. 中国比较医学杂志, 2007, 17(5): 292-296 |
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| 作者姓名： | 王卫 魏强 |
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| 作者单位： | 中国医学科学院,中国协和医科大学实验动物研究所,北京,100021 |
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| 摘 要： | HIV疫苗被认为是预防艾滋病的最有效工具。以前研制的HIV疫苗，大多数能诱导机体产生记忆性B淋巴细胞和持久的抗体，但并不能保护机体免受HIV的感染。记忆性T细胞的研究给研究HIV疫苗提供了新思路。本文着重描述了记忆性T细胞的分群、分化、形成和维持的一般规律及其在HIV疫苗研制中的意义。
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| 关 键 词： | 记忆性T细胞 效应记忆T细胞 中心记忆T细胞 HIV疫苗 |
| 文章编号： | 1671-7856（2007）05-0292-05 |
| 修稿时间： | 2006-07-19 |
Memory T Cell and HIV Vaccine |
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| WANG Wei,WEI Qiang. Memory T Cell and HIV Vaccine[J]. Chinese Journal of Comparative Medicine, 2007, 17(5): 292-296 |
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| Authors: | WANG Wei WEI Qiang |
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| Affiliation: | Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China |
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| Abstract: | The vaccines are considered as an useful approach for preventing the AIDS.Most of the past HIV vaccines only induced the body to product the memory B cell and antibody,but don't to prevent HIV from infecting the body.The strategy on development of vaccines against HIV basing on memory T cells could bring new hope to human vaccination.In this review,the classification,differentiation,formation and duration of memory cells,and also the possible target role for development vaccines will be presented. |
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| Keywords: | Memory T cell Effector memory T cell Central memory T cell HIV vaccine |
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