| HBV携带结核患者抗结核治疗中肝功能变化的临床分析 |
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| 引用本文： | 樊正勤,赵耘,王军,郑强,吴俊杰.HBV携带结核患者抗结核治疗中肝功能变化的临床分析[J].临床肺科杂志,2010,15(3):362-363. |
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| 作者姓名： | 樊正勤 赵耘 王军 郑强 吴俊杰 |
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| 作者单位： | 扬州,扬州市第三人民医院苏北人民医院新区分院,江苏,225000 |
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| 摘 要： | 目的研究乙肝病毒携带结核患者抗结核治疗对肝功能的影响。方法选择我院住院的活动性肺结核患者338例,其中乙肝病毒携带肺结核患者36例,无乙肝病毒携带肺结核患者302例,对抗结核治疗中肝功能变化进行回顾性分析。结果HBV携带结核患者有30.6%出现肝损害,而对照组只有15.9%。HBV阳性组在治疗前ALT分层统计,A组(男≤30U/L,女19≤U/L)与B组(男31～40U/L,女20～40U/L),抗结核治疗后发生肝损害分别为24.1%、57.1%。A、B两组有显著性差异。结论乙肝病毒携带结核患者抗结核治疗易出现肝损害,肝功能ALT正常值上限(ULN)采用男30U/L,女19U/L较目前男女均为40U/L更为安全可靠。
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| 关 键 词： | 乙肝病毒携带 抗结核 肝功能 |
Clinical analysis of changes in liver function of TB patients carrying hepatitis B virus with anti-tuberculosis therapy |
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| FAN Zheng-qin,ZHAO Yun,WANG Jun,ZHENG Qiang,WU Jun-Jie.Clinical analysis of changes in liver function of TB patients carrying hepatitis B virus with anti-tuberculosis therapy[J].Journal of Clinical Pulmonary Medicine,2010,15(3):362-363. |
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| Authors: | FAN Zheng-qin ZHAO Yun WANG Jun ZHENG Qiang WU Jun-Jie |
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| Institution: | FAN Zheng-qin,ZHAO Yun,WANG Jun,ZHENG Qiang,WU Jun-Jie The Third People's Hospital of Yang Zhou,New Area Branch of Subei People's Hospital of Jiangsu Province,Yangzhou City,Jiangsu Province 225000,China |
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| Abstract: | Objective To study anti-tuberculosis therapy on liver function of TB patients carrying hepatitis B virus.Methods The study selected 338 patients with active pulmonary tuberculosis in our hospital,of which 36 cases carrying hepatitis B virus,302 without hepatitis B virus. The data of changes in liver function in the treatment of anti-tuberculosis were retrospectively analyzed.Results Liver damage occurred in 30.6% TB patients carrying hepatitis B virus,while only 15.9% in the control group. In the treatment ... |
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| Keywords: | carrying hepatitis B anti-tuberculosis liver function |
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