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清开灵联合还原型谷胱甘肽治疗药物性肝炎疗效评价
引用本文:梅月志,杨莉明.清开灵联合还原型谷胱甘肽治疗药物性肝炎疗效评价[J].中国热带医学,2010,10(4):477-478.
作者姓名:梅月志  杨莉明
作者单位:东莞市慢性病防治院,广东东莞,523008
摘    要:目的探讨清开灵和还原型谷胱甘肽对药物性肝炎的临床疗效。方法采用前瞻性研究,对2007年6月~2009年5月诊断为抗结核药物性肝炎228例患者随机分为治疗组114例和对照组114例,前者予清开灵和还原型谷胱甘肽治疗,后者进行常规护肝治疗,治疗2~4周对疗效进行统计学分析。结果结核药物性肝炎大多发生于强化期内,治疗组的疗效显著优于对照组,2组间1周内有效率差异有统计学意义(P0.05)。结论清开灵和还原型谷胱甘肽治疗1周内可明显改善药物性肝炎表现及恢复肝功能作用,对于结核药物性肝炎有较好疗效,而且临床应用安全,值得推广应用。

关 键 词:肺结核  药物性肝炎  清开灵  还原型谷胱甘肽

Curative effect of Qingkailing and reductive glutathione on medicamentous liver lesion.
MEI Yue-zhi,YANG Li-ming.Curative effect of Qingkailing and reductive glutathione on medicamentous liver lesion.[J].China Tropical Medicine,2010,10(4):477-478.
Authors:MEI Yue-zhi  YANG Li-ming
Institution:MEI Yue-zhi, YANG Li- ming. (Dongguan Municipal Chronical Disease Hospital,Dongguan 523008,Guangdong,P. R. China)
Abstract:Objective To explore the therapeutic effect of Qingkailing and reductive glutathione on anti-TB-induced hepatitis patients. Methods There 228 inpatients suffered from hepatitis resulted from anti-tuberculous drugs during Jun,2007 and Jun.,2009 were randomly divided into into treatment group and control group each consisted of 114 cases . The former was treated with Qingkailing and reductive glutathione,but the latter was treated with routine drugs. Results The effect in treatment group was markedly over the...
Keywords:Pulmonary tuberculosis/chemotherapy  Hepatitis  Qingkailing  Reductive glutathione  
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