| 玉溪市儿童麻疹疫苗免疫后血清抗体监测分析 |
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| 引用本文： | 杨玉仙,余庆福,杨晓娟,王卫华,李廷学,张耀喜,张丽芳.玉溪市儿童麻疹疫苗免疫后血清抗体监测分析[J].职业与健康,2010,26(24):2907-2909. |
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| 作者姓名： | 杨玉仙 余庆福 杨晓娟 王卫华 李廷学 张耀喜 张丽芳 |
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| 作者单位： | 云南省玉溪市疾病预防控制中心; |
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| 摘 要： | 目的了解玉溪市15岁以下儿童麻疹疫苗免疫后抗体维持情况,为消除麻疹提供科学依据。方法采用分层和整群抽样法,在玉溪市一区八县内随机抽取3个县(红塔区、江川县、元江县),抽中的每个县按PPS概念抽样法调查350名儿童麻疹疫苗免疫接种情况,并采集合格血清进行麻疹IgG抗体检测。结果在调查的1043名儿童中,麻疹抗体阳性率为94.92%,几何平均滴度(GMT)为1:1080.93。三县区的阳性率均在94.68%以上,几何平均滴度(GMT1:)在936.10～1321.56之间,县区之间抗体阳性率无差异;不同年龄段之间抗体阳性率差异有统计学意义(χ2=14.20,P0.01),其中以1岁基础免疫组抗体相对较低,仅达91.91%;性别之间抗体阳性率无差异;不同户籍儿童抗体阳性率差异有统计学意义(χ2=13.52,P0.05)。结论玉溪市儿童麻疹疫苗免疫后产生了有效的IgG保护性抗体,1～15岁儿童形成了较牢固的免疫屏障,对控制麻疹取得较好的作用。
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| 关 键 词： | 麻疹 免疫效果 |
Monitoring of Serum Antibody after Measles Immunization on Children in Yuxi City |
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| YANG Yu-xian,YU Qing-fu,YANG Xiao-juan,WANG Wei-Hua,LI Ting-Xue,ZHANG Yao-xi,ZHANG Li-fang.Monitoring of Serum Antibody after Measles Immunization on Children in Yuxi City[J].Occupation and Health,2010,26(24):2907-2909. |
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| Authors: | YANG Yu-xian YU Qing-fu YANG Xiao-juan WANG Wei-Hua LI Ting-Xue ZHANG Yao-xi ZHANG Li-fang |
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| Institution: | YANG Yu-xian,YU Qing-fu,YANG Xiao-juan,WANG Wei-Hua,LI Ting-Xue,ZHANG Yao-xi,ZHANG Li-fang(Yuxi Center for Disease Control and Prevnetion,Yunnan,653100,China) |
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| Abstract: | Objective]To understand the measles antibody levels of children under 15 years after immunization in Yuxi City,and provide scientific evidence for measles elimination.Methods]Stratified cluster sampling method was adopted to select 3 counties(Hongta District,Jiangchuan County,Yuanjiang County) from Yuxi City,350 from each county were sampled for immunization investigation according to PPS sampling method.The qualified serum samples were collected for measles IgG antibody test.Results]Of1043 surveyed chil... |
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| Keywords: | Measles Immune effect |
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