| 川续断DA303对大鼠子宫的作用 |
| |
| 引用本文： | 龚小健,吴知行.川续断DA303对大鼠子宫的作用[J].中国药科大学学报,1996,27(1):48-51. |
| |
| 作者姓名： | 龚小健 吴知行 |
| |
| 作者单位： | 中国药科大学药理学教研室 |
| |
| 摘 要： | ＤＡ３０３是川续断的一种化学成分，经研究能显著抑制未孕和妊娠大鼠离体子宫肌的自发收缩活性，对抗２．５ｕ／ＬＯｘｙ引起妊娠大鼠离体子宫平滑肌的时相性收缩。ＤＡ３０３并能降低妊娠大鼠在体子宫的自发收缩强度及频率，对抗０．２５ｕ／ｋｇＯｘｙ引起的收缩强度、频率及张力的提高。
|
| 关 键 词： | 川续断 DA303 催产素 离体子宫 在体子宫 |
An Experimental Pulmonary Embolus Model in Rats for Evaluation of Thrombolytic Agents |
| |
| Li Shaoping,Ji Hui,Li Xiaoqiang.An Experimental Pulmonary Embolus Model in Rats for Evaluation of Thrombolytic Agents[J].Journal of China Pharmaceutical University,1996,27(1):48-51. |
| |
| Authors: | Li Shaoping Ji Hui Li Xiaoqiang |
| |
| Abstract: | An experimental pulmonary embolus in rats was obtained by injection of (125)I-radiolabeled clots into the venous circulation.Thrombolytic action was evaluated by determining the radioactivity increasing in the blood. Three thrombolytic agents were tested.Svate-3(0.08 u/ kg.iv)and urokinase(10000 u/kg, iv)significantly increased thrombolysis. Nevin fibrinolytic enzyme produced a dose-related thrombolysis. The results showed that the model is valuable for evaluation of thrombolytic agents. |
| |
| Keywords: | Pulmonary embolus medel 125I-fibrinogen Svate-3 Urokinase Nevin fibrinolytic enzyme |
| 本文献已被 CNKI 维普 等数据库收录！ |
| 点击此处可从《中国药科大学学报》浏览原始摘要信息 |
| 点击此处可从《中国药科大学学报》下载免费的PDF全文 |
