Sequential evaluation of left ventricular myocardial performance in children after anthracycline therapy |
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| Authors: | Ishii M Tsutsumi T Himeno W Eto G Furui J Hashino K Sugahara Y Muta H Akagi T Ando A Eguchi H Kato H |
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| Affiliation: | Department of Pediatrics and the Cardiovascular Research Institute, Kurume University School of Medicine, Japan. masaishi@med.kurume-u.ac.jp |
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| Abstract: | This study prospectively assessed subclinical cardiotoxicity in patients undergoing chemotherapy by using the Tei index combining systolic and diastolic time intervals. A significant difference in the Tei index was observed between patients who received a low dose and those who received a moderate to high dose of anthracycline antibiotic drugs. The Tei index is a sensitive, accurate, and easy approach for detecting subclinical anthracycline cardiotoxicity. |
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