急性液化石油气中毒的临床特征研究

目的 加深对急性液化石油气中毒（ALPGT）的认识，为ALPGT的实验研究提供临床资料。方法 对29例急性液化石油气中毒的临床及影像学资料进行分析，探讨其表现、预后、影像学改变与急性一氧化炭中毒的差异。结果本组病例均在意识障碍恢复后立即出现持续的神经精神症状，表现为明显的认知功能障碍及精神行为异常。头颅MRI改变以双侧大脑皮质对称性异常信号为主，不同于急性一氧化碳中毒以双侧基底节及皮层下白质损害为主。大脑皮质的损害范围与认知障碍的程度相关。结论 急性液化石油气中毒对高级神经功能损害更严重，近期预后差。

Analysis of the clinical characteristics of acute liquid petroleum gas poisoning

Objective To enhance the cognition about the characterization of ALPGT and provide more clinical information for the experimental study. Methods Clinical characters and imaging findings of 29 cases with acute liquid petroleum gas poisoning were analyzed retrospectively. The differences between clinical manifestations, prognosis, imaging findings of acute liquid petroleum gas poisoning and acute carbon monoxide pisoning were investigated. Results Continuing neuropsychological symptoms were observed immediately after the recovery of conscious disturbance in all cases. The main characters were cognitive dysfunction and psychological behavior disturbance. The MRI showed high signal intensity in bilateral cerebral cortex symmetrically on T2WI,FLAISR and )WI. While the lesions of acute carbon monoxide poisoning were bilateral basal ganglia and sub- cortical white aatter. The degree of cognitive dysfunction was related to the impairment dimension of cerebral cortex. Conclusion Acute liquid petroleum gas poisoning is more harmful role to senior neurologic function and short term prognosis was unsatisfactiory.