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右美托咪啶在临床麻醉与镇痛中的应用进展
引用本文:文松,肖智,李瑛.右美托咪啶在临床麻醉与镇痛中的应用进展[J].川北医学院学报,2013,28(6):591-595.
作者姓名:文松  肖智  李瑛
作者单位:遵义医学院研究生学院;遵义医学院医学与生物学研究中心;遵义医学院附属医院麻醉科,贵州,遵义,563099
基金项目:贵州省科学技术基金项目(黔科合J字LKZ[2011]21号)
摘    要:右美托咪啶(dexmedetomidine,DEX)是一种新型的高选择性α2肾上腺素,能受体激动剂,具有镇静、镇痛、抗焦虑等作用。国内外有研究表明DEX可作为术中麻醉和术后镇痛的辅助药,可减少术中麻醉药用量,推迟术后首次需要镇痛药的时间和减少镇痛药用量。本文就此进行综述。

关 键 词:右美托咪啶  麻醉  镇痛

Recent advancement and clinical application of dexmedetomidine in anes-thesia and analgesia
WEN Song,XIAO Zhi,LI Ying.Recent advancement and clinical application of dexmedetomidine in anes-thesia and analgesia[J].Journal of North Sichuan Medical College,2013,28(6):591-595.
Authors:WEN Song  XIAO Zhi  LI Ying
Affiliation:1. Graduate School of Zunyi Medical College;2. Research Center for Medicine & Biology, Zunyi Medical College;3. Department of Anes-thesiology,Affiliated Hospital of Zunyi Medical College, Zunyi 563099, Guizhou, China)
Abstract:Dexmedetomidine is a new and highly selective α2-adrenoceptor agonist,which exhibits sedative as well as analgesic and anxiolytic effects. The researhes at home and abroad proved that dexmedetomidine is used as adjuvant for anesthesia during the surgery and analgesia after the surgery. There is a significant increase in the post-operative analgesia duration before the first analgesia is re-quired and a decrease in the dose required for pain relief. This review aims to present an update clinical application of dexmedetomidine in anesthesia and analgesia.
Keywords:Dexmedetomidine  Anesthesia  Analgesia
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