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柯萨奇B组病毒特异性IgM检测方法的建立及其应用
引用本文:郑连荣,李淑梅,孙立群,周桂敏,朱晓薇. 柯萨奇B组病毒特异性IgM检测方法的建立及其应用[J]. 吉林大学学报(医学版), 1994, 0(3)
作者姓名:郑连荣  李淑梅  孙立群  周桂敏  朱晓薇
作者单位:白求恩医大第二临床学院,吉林省邮电职工医院
摘    要:本文应用免疫酶染色法检测77例病毒性心肌炎患者血清中特异性IgM抗体。检测结果表明,心肌炎组检出率为70.1%,正常对照组检出率为12.5%,两组间P<0.01。同时还检测了血清中和抗体,阳性率为55.8%,对照组为10%,两者差异非常显著。从而证明该法对病毒性心肌炎的诊断较为特异,对于心肌炎的早期诊断,早期治疗及病因学的研究具有指导性意义。

关 键 词:病毒性疾病/诊断,心肌炎/诊断,免疫酶技术,免疫球蛋白M类/分析

Establishment and application of the method for detection of the specific IgM of Coxsackie B virus
Zheng Lianrong,Li Shumei,Zhu Xiaowei,et al. Establishment and application of the method for detection of the specific IgM of Coxsackie B virus[J]. Journal of Jilin University: Med Ed, 1994, 0(3)
Authors:Zheng Lianrong  Li Shumei  Zhu Xiaowei  et al
Abstract:Usingtheimmunoenzyme staining method, we detectedthe specific antibodyIgm in serum of 77 patients with viral myocarditis. the results showed that the detection rate inthe morbid and the control groups were 70.1%and 12.5%respectively. The differenee betweenthese 2 groups was of marked significance(P<0. 01). At the same time, we also detected theserum neu tralization antibody , and the positive rate in the morbid and the control groups were55.8%and 10.0%respectively. the difference between these 2 groups was of marked signifi-cance, Our results revea led that this me thod is specific in d idgnosis for viral myocarditis. thismethod is also of guiding significance in early diagrnosis, early treatment and researches on etiolo-gy of the disease.
Keywords:virus diseases/DI  myocarditis/DI  immunoenzyme ttechnics  Igm/AN  
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