| 2型糖尿病家系青少年一级亲属心血管危险因素研究 |
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| 引用本文： | 刘博伟,尹福在,马春明,陆强,娄东辉,王锐,韩改玲,吴广飞,沈轶,刘波,秦春梅.2型糖尿病家系青少年一级亲属心血管危险因素研究[J].中华糖尿病杂志,2008,16(11):648-650. |
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| 作者姓名： | 刘博伟 尹福在 马春明 陆强 娄东辉 王锐 韩改玲 吴广飞 沈轶 刘波 秦春梅 |
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| 作者单位： | 河北省秦皇岛市第一医院内分泌科,066000 |
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| 基金项目： | 河北省科技厅科技支撑项目(072761528) |
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| 摘 要： | 目的探讨2型糖尿病（T2DM）家族史对青少年心血管危险因素的影响。方法秦皇岛地区12～18岁青少年4023人横断面调查。根据父母有无糖尿病分为糖尿病家族史阳性组（FH＋）和阴性组（FH-）。测量腰围（WC）、血压、FPG、血脂,计算BMI。结果（1）FH＋组腰围、FPG、TC和LDL-C均高于FH-组（P〈0.05）,超重/肥胖、高SBP、高FPG检出率高于FH-组（P〈0.05）。（2）校正年龄、性别后FH＋组SBP、FPG升高、超重/肥胖的危险性分别是FH-组的1.54、2.06、1.33倍,95%CI分别是（1.10～2.16）、（1.46～2.89）、（1.12～1.59）,具有2项以上心血管危险因素的危险性是FH-组的1.72倍。结论T2DM患者的青少年一级亲属已存在心血管危险因素增加和聚集。应重视对这一人群进行早期筛查和干预,以减少心血管病的发生。
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| 关 键 词： | 糖尿病 2型 家族史 一级亲属 青少年 心血管危险因素 |
Study on risk factors for cardiovascular disease in adolescents with a family history of type 2 diabetes |
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| LIU Bo-wei,YIN Fu-zai,MA Chun-ming,et al..Study on risk factors for cardiovascular disease in adolescents with a family history of type 2 diabetes[J].CHINESE JOURNAL OF DIABETES MELLITUS,2008,16(11):648-650. |
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| Authors: | LIU Bo-wei YIN Fu-zai MA Chun-ming |
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| Institution: | LIU Bo-wei,YIN Fu-zai,MA Chun-ming,et al.Department of Endocrinology,the First Hospital of Qinhuangdao,Hebei Medical Univesity,Qinhuangdao 066000,China |
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| Abstract: | Objective To explore the risk factors for cardiovascular disease in adolescents with a family history of type 2 Diabletes.Methods A cross-sectional study was conducted in 4023 adolescents aged 12-18 years.They were divided into two groups with(FH+)and without(FH-)family history of diabetes and measurements included BMI,waist circumference,blood pressure and fasting plasma glucose(FPG),total cholesterol(TC),triglyceride(TG)and high-density lipoprotein cholesterol(HDL-C).Results When compared with FH-group,FH... |
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| Keywords: | Diabetes type 2 Family history First degree relative Adolescent Risk factors for cardiovascular disease |
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