植物代谢组学技术在山西道地药材研究中的应用

以柴胡、款冬花、远志等山西道地中药材为例，总结植物代谢组学技术在中药材质量评价中的应用。在中药材质量评价中，代谢组学侧重于对样本的客观分组聚类，同时可确定差异代谢物，与指纹图谱技术具有明显的互补性，可使中药质量标准更体现中药特色，提高其可控性。分析该技术的优势与应用前景，指出尚存在的问题和改进建议，为扩大其应用提供参考。

Application of plant metabolomic technology in study on several Shanxi genuine medicinal materials

The application of plant metabolomic technology in the quality evaluation of traditional Chinese medicinal materials (TCMM) was reviewed, using Buplerui Radix, Farfarae Flos, Polygale Radix, and Astragali Radix as genuine medicinal materials. In quality evaluation of TCMM, not only the cluster, but also the differential metabolites between different groups could be revealed simultaneously by metabolomic technology. Thus, plant metabolomic technology is complimentary with fingerprint technology, the characteristics of TCMM could be reflected in quality standards, and the controllability could be also improved. The advantage as well as the prospect is discussed. In addition, the limitations of this technique are pointed and the improvement methods are also suggested.