| 沙海参中的三个海参皂苷 |
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| 引用本文： | 翁怡毅,易杨华,李玲,张诗龙,潘敏翔,刘宝姝,路小娟,薛梅.沙海参中的三个海参皂苷[J].中国天然药物,2007,5(2):96-100. |
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| 作者姓名： | 翁怡毅 易杨华 李玲 张诗龙 潘敏翔 刘宝姝 路小娟 薛梅 |
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| 作者单位： | 第二军医大学海洋药物研究中心,上海200433 |
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| 基金项目： | 国家高技术研究发展计划(863计划) |
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| 摘 要： | 目的：研究沙海参体内的化学成分，寻找结构新颖的三萜皂苷类化合物。方法：应用多种色谱技术对沙海参体内的化学成分进行分离纯化，根据化合物的理化性质和波谱数据鉴定其结构。结果：分离得到三个三萜皂苷化合物，分别为arenicolaside A（1），fuscocineroside C（2）和holothurin A（3）。结论：化合物1为一个新的三萜皂苷化合物，化合物2、3均为首次从沙海参中分离得到.
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| 关 键 词： | 沙海参 海参 三萜皂苷 |
| 文章编号： | 1672-3651（2007）02-0096-05 |
| 修稿时间： | 2006-11-15 |
Three Triterpene Glycosides from Sea Cucumber Hologhuria arenicola Semper |
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| WENG Yi-Yi,YI Yang-Hua,LI Ling,ZHANG Shi-Long,PAN Min-Xiang,LIU Bao-Shu,LU Xiao-Juan,XUE Mei.Three Triterpene Glycosides from Sea Cucumber Hologhuria arenicola Semper[J].Chinese JOurnal of Natural Medicines,2007,5(2):96-100. |
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| Authors: | WENG Yi-Yi YI Yang-Hua LI Ling ZHANG Shi-Long PAN Min-Xiang LIU Bao-Shu LU Xiao-Juan XUE Mei |
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| Institution: | Research Center for Marine Drugs, Second Military Medical University, Shanghai 200433, China |
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| Abstract: | ATM:To study the constituents of the sea cucumbe Holothuria arenicola Semper.METHOD:Triterpene glycosides from Holothuria arenicola Semper were separated and purified by silica gel chromatography,reversed-phase silica gel chromatography and reversed-phase HPLC.Their structures were elucidated on the basis of chemical evidence and spectral data.Three triterpenes were identified as arenicolaside A(1),fuscocineroside C(2)and holothurin A(3).RESULTS:Arenicolaside A(1)is a new triterpene glycoside.Compounds 2 and 3 were isolated from Holothuria arenicola Semper for the first time. |
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| Keywords: | Holothuria arenicola Semper Holothurian Triterpene glycoside |
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