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In Vitro Effect of Oxidized Dextrans on Peritoneal Cells
Authors:V. A. Shkurupiy  S. A. Arkhipov  A. V. Troitsky  N. G. Luzgina  M. V. Zaikovskaja  E. P. Gulyaeva  T. N. Bistrova  E. G. Ufimceva  D. A. Iljin  E. S. Akhramenko
Affiliation:(1) Research Center of Clinical and Experimental Medicine, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia
Abstract:We studied the dependence of in vitro dextran biocompatibility on the method of oxidation of 35-kDa dextran. The biocompatibility of dextran oxidized with potassium permanganate was higher compared to that obtained by radiochemical oxidation. It was related to the formation of peroxide compounds during radiochemical oxidation. Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Suppl. 1, pp. 120–122, 2008
Keywords:oxidized dextran  biocompatibility  peritoneal cells  macrophages
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