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老年高血压患者不同心室构型与氮末端B型脑钠肽前体的相关性
引用本文:高鹏,朱启伟,杜瑞雪,骆雷鸣.老年高血压患者不同心室构型与氮末端B型脑钠肽前体的相关性[J].中国康复理论与实践,2011,17(5):454-456.
作者姓名:高鹏  朱启伟  杜瑞雪  骆雷鸣
作者单位:解放军总医院南楼心血管二科,北京市,100853
摘    要:目的分析老年高血压患者不同心脏构型之间的氮末端B型脑钠肽前体(NT-proBNP)水平差异。方法检查老年高血压患者326例,正常人265名NT-proBNP水平,通过超声测量,按Ganau分类法,将高血压组左心室质量指数升高的患者分为向心性肥厚型、离心性肥厚型两种构型。结果高血压病组NT-proBNP水平高于对照组。按心脏重构分组后,向心性肥厚组NT-proBNP水平升高最多,离心性肥厚组次之,而正常构型组和向心性重构组与对照组没有显著性差异。结论老年高血压患者在未出现心功能失代偿时NT-proBNP已出现明显升高,且不同构型之间NT-proBNP水平不同,提示NT-proBNP可能参与左心室的重构甚至是心功能的恶化。

关 键 词:高血压  老年  左心室质量指数  氮末端B型脑钠肽前体

Relationship between N-terminal-pro-B-type Natriuretic Peptide and Left Ventricular Mass Index in Elderly Hypertension Patients
GAO Peng,ZHU Qi-wei,DU Rui-xue,et al..Relationship between N-terminal-pro-B-type Natriuretic Peptide and Left Ventricular Mass Index in Elderly Hypertension Patients[J].Chinese Journal of Rehabilitation Theory and Practice,2011,17(5):454-456.
Authors:GAO Peng  ZHU Qi-wei  DU Rui-xue  
Institution:GAO Peng,ZHU Qi-wei,DU Rui-xue,et al.the 2nd Department of Cardiology,Southern Building Clinic Division,Chinese PLA General Hospital,Beijing 100853,China
Abstract:Objective To investigate the N-terminal-pro-B-type natriuretic peptide(NT-proBNP) concentration in the difference myocardial wall motion after essential hypertension.Methods 326 patients with essential hypertension and normal heart function and 265 control subjects were measured with their NT-proBNP.According to Canau's categories,the ventricle geometries of patients with high left ventricular mass index were divided into 2 groups.Results NT-proBNP was significantly higher in patients with hypertension than...
Keywords:hypertension  elderly  left ventricular mass index  N-terminal-pro-B-type natriuretic peptide  
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