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| 土茯苓内生芒果球座菌菌丝体的化学成分研究 | |
| 引用本文： | 梁法亮,李冬利,陶美华,张德志,章卫民. 土茯苓内生芒果球座菌菌丝体的化学成分研究[J]. 广东药学院学报, 2011, 27(3): 256-259. DOI: 10.3969/j.issn.1006-8783.2011.03.011 |
| 作者姓名： | 梁法亮 李冬利 陶美华 张德志 章卫民 |
| 作者单位： | 1. 广东药学院药科学院,广东广州510006;广东省微生物研究所广东省菌种保藏与应用重点实验室/广东省微生物应用新技术公共实验室/广东省华南应用微生物重点实验室-省部共建国家重点实验室培育基地,广东广州510070 2. 广东省微生物研究所广东省菌种保藏与应用重点实验室/广东省微生物应用新技术公共实验室/广东省华南应用微生物重点实验室-省部共建国家重点实验室培育基地,广东广州,510070 3. 广东药学院药科学院,广东广州,510006 |
| 基金项目： | 广东省自然科学基金项目，广州市科技计划项目，广东省科学院优秀青年科技人才基金 |
| 摘 要： | 目的 研究药用植物土茯苓内生芒果球座菌菌丝体的化学成分.方法 利用正相硅胶柱层析、C18反相硅胶柱层析、Sephadex LH-20凝胶柱层析以及制备薄层层析等色谱方法进行分离纯化,根据理化性质及光谱数据确定化合物的结构.结果 从土茯苓内生芒果球座菌菌丝体中分离并鉴定出7个化合物,分别为:脑苷脂D(1)、腺苷(2)、(... |
| 关 键 词： | 土茯苓 芒果球座菌 内生真菌 化学成分 |
Chemical constituents of the mycelia of Guignardia mangiferae, an endophyte from Smilax glabra |
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| LIANG Fa-liang,LI Dong-li,TAO Mei-hua,ZHANG De-zhi,ZHANG Wei-min. Chemical constituents of the mycelia of Guignardia mangiferae, an endophyte from Smilax glabra[J]. Academic Journal of Guangdong College of Pharmacy, 2011, 27(3): 256-259. DOI: 10.3969/j.issn.1006-8783.2011.03.011 | |
| Authors: | LIANG Fa-liang LI Dong-li TAO Mei-hua ZHANG De-zhi ZHANG Wei-min |
| Affiliation: | 1.School of Pharmacy,Guangdong Pharmaceutical University,Guangzhou 510006,China;2.State Key Laboratory of Applied Microbiology(Ministry-Guangdong Province Jointly Breeding Base)/South China,Guangdong Open Laboratory of Applied Microbiology/Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application,Guangdong Institute of Microbiology,Guangzhou 510070,China) |
| Abstract: | Objective To study on the chemical constituents of the mycelia of endophytic Guignardia mangiferae from Smilax glabra.Methods The compounds were isolated and purified by various chromatographic methods such as silica gel,reverse silica gel,sephadex-LH20 and preparative TLC.Their structures were determined extensive analysis of their spectroscopic data as well as by comparison with literature reports.Results Seven compounds were isolated and identified as cerebroside D（1）,adenosine（2）,（22E,24R）-24-methylcholesta-5,22-diene-3β-ol（3）,ergosterol peroxide（4）,（22E,24R）-5α,8α,-epidioxyergosta-6,9,22-triene-3β-ol（5）,22E,24R-5α,6α-epoxyergosta-8,22-diene-3β,7α-diol（6） and cerevisterol（7）.Conclusion All the compounds are isolated from the genus of Guignardia for the first time. |
| Keywords: | Smilax glabra Guignardia mangiferae endophytic fungi chemical constituents |
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