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Deep Brain Stimulation of the Globus Pallidus in a 7-Year-Old Girl with DYT1 Generalized Dystonia
Authors:Seon Tak Jin   Myung Ki Lee   Ju Young Ghang   Seong Man Jeon
Affiliation:1Department of Neurosurgery, Maryknoll Medical Center, Busan, Korea.;2Department of Neurosurgery, Bongseng Memorial Hospital, Busan, Korea.
Abstract:The experience of pediatric deep brain stimulation (DBS) of the globus pallidus internus (GPi) in the treatment of early-onset DYT1 generalized dystonia is still limited. Here, we report the surgical experience of bilateral GPi-DBS under general anesthesia by using microelectrode recording in a 7-year-old girl with early-onset DYT1 generalized dystonia. Excellent improvement of her dystonia without neurological complications was achieved. This case report demonstrates that GPi-DBS is an effective and safe method for the treatment of medically refractory early-onset DYT1 generalized dystonia in children.
Keywords:Globus pallidus   DYT1   Dystonia   Deep brain stimulation
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