Detection of anti-B antibodies in a patient with A1B blood group: A case report and literature review |
| |
| Affiliation: | 1. Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea;2. Department of Laboratory Medicine, Seoul National University Hospital, Seoul, South Korea;3. Department of Laboratory Medicine, Kangdong Sacred Heart Hospital, Seoul, South Korea;1. Department of Transfusion Medicine, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Homi Bhabha National Institute, Navi Mumbai 410210, India;1. Carter BloodCare, Bedford, TX, United States;2. Department of Radiology (Neuroradiology), UT Southwestern Medical Center, Dallas, TX, United States;3. Department of Pathology, UT Southwestern Medical Center, Dallas, TX, United States;4. Department of Internal Medicine (Hematology/Oncology), UT Southwestern Medical Center, Dallas, TX, United States;1. Servizio di Immunoematologia e Medicina Trasfusionale, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy;2. Bone Marrow Transplantation, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy;1. SAINBIOSE-INSERM_U1059, faculty of medicine, University of Saint-Etienne, Saint-Etienne, France;2. Coordinating Haemovigilance Centre and Surveillance of Transfusion (SKAEM), Hellenic National Public Health Organization, Athens, Greece;3. Croatian Institute of Transfusion Medicine, Zagreb, Croatia;1. Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;2. Department of Nursing, School of Medical Sciences, Islamic Azad University, Mashhad Branch, Mashhad, Iran;3. Student of PhD, Department of Pediatric Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran;4. Department of Midwifery, School of Medical Sciences, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran |
| |
| Abstract: | ABO antibodies occur naturally and usually exist as alloantibodies. They are the most clinically significant in cases of transfusions. However, there are very few reports on auto-anti-A or B. A 58-year-old man visited our hospital for evaluation of an inguinal mass. Blood typing was performed, while preparing the patient for an excisional biopsy. Forward and reverse typing showed a typical AB and A pattern. Results of the direct antiglobulin and unexpected antibody screening tests were negative. The serum did not react with AB3 cells. The biopsy revealed a diffuse large B-cell lymphoma. After completing four cycles of R-CHOP chemotherapy, the patient achieved complete remission. There were no anti-B antibodies found on repeat ABO typing. This report shares our experience on unexpected anti-B antibody findings in a patient with an A1B blood type. To the best of our knowledge, this is the first report of anti-B antibodies in a patient with an A1B blood type in Korea. |
| |
| Keywords: | Anti-B ABO discrepancy ABO blood group Blood group typing |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
