Plasma lipemia: When the blood donor becomes a patient |
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| Institution: | 1. Nam?k Kemal University Medical School, Department of Internal Medicine, Division of Hematology, Tekirdag, Turkey;2. Memorial Bahcelievler Hospital Adult Hematology and BMT Clinic, Istanbul, Turkey;3. Yuzuncu Y?l University Medical School, Department of Internal Medicine, Division of Hematology, Van, Turkey;4. Sanko University Medical School, Department of Internal Medicine, Division of Hematology, Gaziantep, Turkey;5. Mugla S?tk? Kocman University Medical School, Department of Internal Medicine, Division of Hematology, Mugla, Turkey;6. Ege University Medical School, Department of Internal Medicine, Division of Hematology, Izmir, Turkey;7. Medicalpark Hospital, Hematology and BMT Clinic, Izmir, Turkey;8. Celal Bayar University Medical School, Department of Internal Medicine, Division of Hematology, Manisa, Turkey;9. Erciyes University Medical School, Department of Internal Medicine, Division of Hematology, Kayseri, Turkey;10. Hacettepe University Medical School, Department of Internal Medicine, Division of Hematology, Ankara, Turkey;11. Ondokuz Mayis University Medical School, Department of Internal Medicine, Division of Hematology, Samsun, Turkey;12. Dicle University Medical School, Department of Internal Medicine, Division of Hematology, Diyarbakir, Turkey;13. Dokuz Eylul University Medical School, Department of Internal Medicine, Division of Hematology, Izmir, Turkey;1. Department of Transfusion Medicine, Government Medical College and Hospital, Chandigarh, India;2. Department of Pathology, Government Medical College and Hospital, Chandigarh, India;1. Division of Transfusion Medicine, Department of Pathology, Microbiology and Immunology. Vanderbilt University Medical Center, 1211 Medical Center Drive, Nashville, TN 37232, USA;2. Vanderbilt Pathology Program in Global Health, Vanderbilt University Medical Center, 1211 Medical Center Drive, Nashville, TN 37232, USA;3. Division of Hematology-Oncology, Department of Internal Medicine, Vanderbilt University Medical Center, 1211 Medical Center Drive, Nashville, TN 37232, USA;1. Department of Pediatrics, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey;2. Department of Pediatric Critical Care Medicine, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey;3. Department of Pediatric Gastroenterology, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey;4. INTERGEN Genetic and Rare Diseases Diagnosis Research and Application Center, Ankara, Turkey;5. Department of Pediatric Endocrinology, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey |
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| Abstract: | Lipemic plasma donations are not a strange phenomenon to blood bankers. According to quality standards for plasma fractionation, lipemic plasma donations must be discarded. Beyond quality control and inventory aspects, plasma lipemia is also an important risk factor for cardiovascular diseases, acute pancreatitis and is associated with overall mortality, however little attention is given to the management of these donors in the literature.A retrospective analysis of every whole blood donation that yielded lipemic plasma between January 1st 2018 and December 31st 2019 was made. The medical examination and donor history for the respective donation was reviewed and the available data was collected regarding hour of donation, gender, age, drugs and coexisting pathologies. Whether the donor was called back for a follow up evaluation regarding the lipemic plasma was also noted.Our blood center received 18274 whole blood donations of which 115 (0,63 %) were reported as having plasma lipemia, in the period of this study. Of these 115 donors, 103 (89,57 %) were male. The average age was 47,63 ± 10,65 years. A clear peak in lipemic plasma donations 4 hours after the classic lunch hours is visible. For 88,70 % of the donors, this was the first time their hypertriglyceridemia was identified.The nonfasting elevation of plasma triglycerides in these donors represents a true metabolic derangement. This is a golden opportunity for early intervention and follow up evaluation is indicated. More attention must be given during the medical evaluation to properly identify donors at risk of lipemic donations. |
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| Keywords: | Blood donors Blood banks Plasma Lipid metabolism disorders Hypertriglyceridemia |
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