Safety and efficacy of subcutaneous night-time only apomorphine infusion to treat insomnia in patients with Parkinson's disease (APOMORPHEE): a multicentre,randomised, controlled,double-blind crossover study |
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| Affiliation: | 1. Sleep and Neurology Department, Beau Soleil Clinic and EuroMov, Digital Health in Motion, University of Montpellier, Montpellier, France;2. Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, Paris, France;3. Department of Neurology, University Hospital of Nîmes, Nîmes, France;4. Sleep Department, University Hospital of Nîmes, Nîmes, France;5. Department of Neurology, Pontchaillou University Hospital, Université de Rennes 1, Rennes, France;6. Sleep Department, Polyclinique Rennes Saint-Laurent, Rennes, France;7. Clinical Neurophysiology Department, INSERM, CIC1413, Nantes, France;8. University Hospital of Nantes, INSERM, CIC1413, Nantes, France;9. Hôpital d’Instruction des Armées Percy, Clamart, France;10. Department of Neurology, University Hospital of Strasbourg, Strasbourg, France;11. Genetic Institute and Molecular and Cellular Biology (IGBMC), INSERM-U964/CNRS-UMR7104 Strasbourg University, Illkirch, France;12. Federation of Translational Medicine of Strasbourg (FMTS), Strasbourg University, Strasbourg, France;13. Sleep Department, Pergola Clinic, Vichy, France;14. APHM, CHU Timone, Department of Neurology and Movement Disorders, and Aix-Marseille Université, CNRS, INT, Institute of Neuroscience, Timone, Marseille, France;15. Sleep Unit, Epileptology Department, Timone Hospital, Marseille, France;p. EA 7280, UFR Medicine, University of Clermont Auvergne, Clermont-Ferrand, France;q. Neurology Department, CHU, and INP, Institut Pascal, Clermont-Ferrand France;r. University of Lille, INSERM, CHU Lille, LilNCog, Lille Neuroscience and Cognition, INSERM, UMR-S1172, Lille, France;s. Department of Epidemiology and Biostatistics, Beau Soleil Clinic, Montpellier, France;t. AP-HP, Salpetriere Hospital, DMU Neuroscience 6, Paris, France;u. Sorbonne University, Paris Brain Institute, INSERM, CNRS, Paris, France;v. Adaptation Biologique et Vieillissement (UMR8256), Institut de Biologie Paris Seine, Sorbonne University, CNRS, Paris France |
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