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| 正交设计优选舒心胶囊原料药的水提工艺 | |
| 引用本文： | 许利平,杨剑芳,王欣苗,于萍,王燕,穆阳,庞鑫.正交设计优选舒心胶囊原料药的水提工艺[J].成都中医药大学学报,2009,32(4). |
| 作者姓名： | 许利平 杨剑芳 王欣苗 于萍 王燕 穆阳 庞鑫 |
| 作者单位： | 1. 首都医科大学中医药学院,北京,100069 2. 北京市农林科学院植物保护环境保护研究所,北京,100097 3. 北京海虹药通电子商务有限公司,北京,100120 4. 北京市门头沟区中医医院药剂科,102300 |
| 基金项目： | 北京市优秀人才培养专项经费D类资助(2003-2007:820039); 北京市属市管高等学校人才强教计划资助项目(BAHED2006) |
| 摘 要： | 目的:研究舒心胶囊原料药提取挥发油后的最佳水提工艺条件.方法:采用高效液相色谱法,用70%甲醇回流提取制样用作阿魏酸含量测定的方法学考察;采用L9(34)正交试验设计,以阿魏酸含量和浸膏收得率为指标,对舒心胶囊原料药的水提工艺进行优选.结果:舒心胶囊原料药中阿魏酸含量为0.0701.影响提取的主次因素为:提取次数＞加水量＞提取时间;优选得到的最佳提取条件为:加6倍量水提取3次,每次提取0.5 h.结论:该工艺稳定,重复性好,适合于舒心胶囊原料药提取挥发油后药渣的水提条件. |
| 关 键 词： | 舒心胶囊 正交试验 提取工艺 阿魏酸 |
Extraction Process with Water of Shuxin Capsule in the Raw Materials Selected by Orthogonal Experiment |
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| XU Li-ping,YANG Jian-fang,WANG Xin-Miao School of TCM,Capital University of Medical Sciences,Beijing ,China.Extraction Process with Water of Shuxin Capsule in the Raw Materials Selected by Orthogonal Experiment[J].Journal of Chengdu University of Traditional Chinese Medicine,2009,32(4). | |
| Authors: | XU Li-ping YANG Jian-fang WANG Xin-Miao School of TCM Capital University of Medical Sciences Beijing China |
| Institution: | XU Li-ping1,YANG Jian-fang2,WANG Xin-Miao11 School of TCM,Capital University of Medical Sciences,Beijing 100069,China,2 Institute of Plant , Environment Protection,Beijing Academy of Agriculture , Forestry Sciences,Beijing 100097,3 Beijing Haihong Drug E-commerce Co.,Ltd.Beijing 100120,4 Beijing Mentougou TCM Pharmacy,Beijing 102300 |
| Abstract: | Objective: To determine extracting process with water of Shuxin Capsule stuff after the extracting of volatile oil.Methods: The measurement method of ferulic acid was determined by HPLC using samples refluxed with 70% methanol.The optimum extraction conditions were investigated by orthogonal design using the extract weight and the content of ferulic acid as two indexes.Results: The content of ferulic acid in the raw materials of Shuxin Capsule was 0.070%.The factors influencing the effect in decreasing orde... |
| Keywords: | Shuxin Capsule orthogonal experiment extraction process ferulic acid |
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