胆囊腺肌瘤病20例临床病理分析

目的:探讨胆囊腺肌瘤病的临床病理特点。方法:对817例胆囊切除标本中病理确诊的20例胆囊腺肌瘤病的临床资料进行回顾性分析。结果:20 例胆囊腺肌瘤病临床表 与慢性胆囊炎胆石症类似。病变大体形态:局限型11例(均位于胆囊底部)、节段型7例和弥漫型2例。组织学特征为胆囊黏膜上皮增生、上皮陷于肌层或浆膜下形成数量较多的罗 阿氏窦、以及肌层增生肥厚。结论:胆囊腺肌瘤病是一种好发于成年女性的瘤样病变,此病常与慢性胆囊炎、胆石症并存,临床诊断困难,确诊需依赖病理检查。

Clinicopathological analysis of 20 cases of adenomyomatosis of the gallbladder

OBJECTIVE:To study the clinicopathological features of adenomyomatosis of gallbladder(GBA). METHODS: Retrospective histopathologic analysis was performed in 20 cases of GBA arisen from 817 cholecystectomy specimens. RESULTS: The clinical manifestation of the patients with GBA was similar to that of the chronic cholecystitis or cholelithiasis.Grossly,there were three growth patterns of the lesion,localized,segmental and diffused types.The main histopathologic features showed the mucosal hyperplasia forming many Rokitansky-Aschoff(R-A)sinus and hypertrophy of the muscular layer. CONCLUSIONS: GBA is a tumor-like lesion that occurs predominantly in adult women.It frequently coexists with chronic cholecystitis and cholelithiasis.It is difficut to make the diagnosis for clinicians.Pathological confirmation of the diagnosis is always needed.