基底动脉尖综合征20例临床分析

目的探讨基底动脉尖综合征的病因、临床表现、影像学特征及治疗与预后。方法对20例基底动脉尖综合征患者的临床资料进行回顾性分析。结果基底动脉尖综合征以老年患者为主，病因及高危因素有高血压、糖尿病、高血脂及心脏病等，临床常见眩晕、意识障碍、眼球运动障碍、瞳孔异常及运动障碍。影像学特征常为中脑或丘脑合并枕叶、颞叶、小脑等部位的梗死，尤以双侧丘脑“蝶形”梗死灶为特征性改变。本病预后不良。结论基底动脉尖综合征的诊断主要依据临床及影像学表现，早期全面综合治疗，可以提高生存率。

Clinical analysis of 20 patients with top of the basilar artery syndrome

Objective To investigate the etiological factor,clinical manifestation,imaging feature ,treatment and prognosis of top of the basilar artery syndrome（TOBS）. Methods The clinical date of 20 cases were analyzed. Results Most of the cases were old aged. The etiological and high risk factors included hypertension, diabetes, hypereholcsrerol, heart disease and so on. The clinical manifestation comprised the vertigo, unconsciousness, disturbance of eyeballs, abnormality of pupils and movement disorders. Imaging feature showed that TOBS was infarction in midbrain or thalamencephalon unite occipital lobes,temporal lobes and cellebellum, especially the most important change was the infarction like butterfly in both sides of thalamencephalon. The prognosis of TOBS was bad. Conclusion Our diagnose TOBS mainly depends on the clinical manifestation and imaging feature. Early comprehensive treatment may improve the survival rate of the TOBS.