纳洛酮治疗急性酒精中毒30例疗效观察

目的观察纳洛酮治疗急性酒精中毒的有效性及安全性。方法60例急性酒精中毒患者随机分为2组，治疗组30例采用纳洛酮治疗，对照组30例采用补液利尿常规治疗，比较两组的清醒时间。结果纳洛酮治疗急性酒精中毒清醒时间明显较对照组提前（P〈0．01），且未发现副作用。结论纳洛酮治疗急性酒精中毒安全有效，值得推广。

Clincal observatain of naloxone in treating acute alcoholism

Objective To observe the efficacy and safety of Naloxone in treating acute alcoholism. Methods 60 cases of acute alcoholism were randomly divided into the experimental group （ n = 30） and the control group （ n = 30 ）. Patients in the experimentalgroup were treated with Naloxone, and patients in the other group were treated with conventianonal therapy, including fluid replacement plus diuretic agent. The time of regaining consciousness in each group were noted. Results The time of regaining consciousness was shorter in the Naloxone treatment group than that in control group, obviously （ P 〈 0. 01 ）. And no abverse event occurred. Conclusion Naloxone could be widely used in treating acute alcoholism, with good curative effect and safety.