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Reference values for renal concentrating capacity in children by the desmopressin test
Authors:Staffan Mårild  Ulf Jodal  Gun Jonasson  Lena Mangelus  Anders Odén  Nils-Gunnar Persson
Affiliation:(1) Department of Paediatrics, University of Gothenburg, Östra sjukhuset, S-416 85 Gothenburg, Sweden;(2) Department of Mathematical Statistics, University of Gothenburg, Östra sjukhuset, S-416 85 Gothenburg, Sweden
Abstract:Reference values are reported for maximal renal concentrating capacity in children using intranasally administered desmopressin. The report is based on 591 tests in 473 healthy children aged 0.5–13 years. The concentrating capacity increased markedly during the first years of life and reached a plateau at the age of 3 years. The mean value minus two standard deviations was 525 mosmol/kg at 1 year of age and 825 mosmol/kg at 3 years of age.
Keywords:Renal concentrating capacity  Desmopressin
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