CEREBRO-SPINAL INFARCTION CAUSED BY ATHEROMATOUS EMBOLI |
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| Authors: | Chikao Yutani Masami IMAKITA Hatsue ISHIBASHI-UEDA Kaoru Hatanaka Riichiro Waki Makoto Ogawa Toru Sawada Takenori Yamaguchi |
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| Affiliation: | Division of Pathology, National Cardiovascular Center, Osaka;Department of Pathoetiology, Research Institute, National Cardiovascular Center, Osaka;Department of Internal Medicine National Cardiovascular Center, Osaka |
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| Abstract: | Cholesterol embolization to the abdominal viscera is common, but rare in the central nervous system. Fourteen cases of atheromatous embolization to the central nervous system were morphologically investigated. Among the 800 consecutive autopsy cases, 38 cases had atheromatous emboli in various organs. Cerebro-spinal infarction caused by atheromatous emboli was found in 11 cases. Infarction rate (11/14) was relatively higher than in other organs and 5 of these cases were thought to be due to direct injury to the erosive surface of the aorta; cardiac catheterization (2 cases), intra-aortic baloon pumping (2 cases), and extra-anatomical bypass graft operation (1 case). These 14 patients consisted of elderly patients (70.1 ±6.3 years old) usually associated with hypertension (78.6%) and diabetes mellitus (42.8%). Anatomically, aortic aneurysms were seen in 10 cases (71.4%), in which aortic arch aneurysm was seen in 6 cases. Hence, aortic mechanical procedure is of great importance for denuding atheromatous materials from erosive atherosclerosis to the central nervous system. ACTA PATHOL. JPN. 35 : 789–801, 1985. |
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