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脑梗死患者血小板颗粒膜糖蛋白CD62p的变化及临床意义
引用本文:王玉兰,陈利民,崔旦旦,邱国强,吴浩清. 脑梗死患者血小板颗粒膜糖蛋白CD62p的变化及临床意义[J]. 江苏大学学报(医学版), 2002, 12(6): 565-566
作者姓名:王玉兰  陈利民  崔旦旦  邱国强  吴浩清
作者单位:常州第一人民医院神经内科,江苏,常州,213003
摘    要:目的:探讨脑梗死患者血浆CD62p水平的变化和其在脑缺血损伤中的作用。方法:用流式细胞术检测150例脑梗死患者及30例正常对照血血浆CD62p含量变化。结果:发病后各组血浆CD62p含量显著升高,并且在脑梗死不同病程时的差异有显著意义,结论:CD62p参与了缺血性脑损伤的病理过程,可作为判断病情的指标。

关 键 词:脑梗死 活化血小板 膜糖蛋白
文章编号:1671-7783(2002)06-0565-02
修稿时间:2002-05-21

Changes of Platelet Surface Glycoproteins CD62p in Plasma of Patients with Cerebral Infarction and Its Clinical Significance
WANG Yu-lan,CHEN Li-min,CUI Dan-dan,et al. Changes of Platelet Surface Glycoproteins CD62p in Plasma of Patients with Cerebral Infarction and Its Clinical Significance[J]. Journal of Jiangsu University Medicine Edition, 2002, 12(6): 565-566
Authors:WANG Yu-lan  CHEN Li-min  CUI Dan-dan  et al
Abstract:Objective:To study the levels of CD 62p in plasma of patients with cerebral infarction and its effect in cerebral ischemic damage. Methods:Platelet surface glycoprotein CD 62p in 150 patients with cerebral infarction and 30 nomal person were measured by flow cytometry.Results:The levels of CD 62p in plasma of patients with cerebral infarction were increased significantly.The differences were significant in acute and relief phases.Conclusion:CD 62p plays a role in the occurance and development of cerebral ischemic damage.
Keywords:Cerebral infarction  Activated platelet membrance  Glycoproteins
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