儿童单眼视力缺陷的图形视觉诱发电位分析

目的：研究图形视觉诱发电位（P－VEP）判断儿童单眼视功能的三种方法（波幅差异比率法、波幅比率法、潜伏斯差异法）的敏感度和特异度，以寻找一种可靠、 有效的发现儿童单眼视力缺陷的VEP视力评估手段。方法：用P－VEP检查了178名正常儿童，建立每一种方法的正常值范围。用P－VEP测定两组具有单眼疾患的儿童（一组患眼视力正常，另一组患眼视力异常）。评估每种方法的敏感度和特异度。结果：三种方法在各年龄组均具有较高的特异度（0．83－0．94）。波幅差异比率法的敏感度在各年龄组均明显高于波幅比率法和潜伏期差异法。结论：VEP波幅差异比率法估计视力，在各年龄组均具有较高的敏感度和特异度，因而是发现单眼视力缺陷的较好的分析指标。

The visually evoked potential test in pediatric monocular acuity deficits

Objective Three methods of evaluating data from the visually evoked potential acuity test-amplitude ratio,amplintde difference,and latency difference-were used and compared for detecting monocular acuity impairment in pediatric patients.Methods To compare the accuracy of each method,normative data were obtained from 178 infants and childrn ranging in age from 5 to 120 months by pattern reversal visually evoked potentials.Two groups of vision pediatric patient were also studied by pattern reversal visually evoked potentials.One group of these patients with low vision in the affected eye;the other group had clinically determined normal vision in the affected eye.The sensitivity and specificity of each method were evaluated in both groups.Results Specificity was high for all methods,ranging from 0.83 to 0.94.The amplitude ratio and latency differnce methods demonstrated low sensitivity to monocyular acuity deficits in all age groups.The sensitivity of the amplitude difference method was significantly higher than that of the other two methods of analysis in all age groups.Conclusions The conclusion of this study is that of the three methods used and compared,amplitude difference is the most useful for detecting monocular acuity impairment in the clinical setting.