原发性高颅压垂体和蝶鞍形态改变机制及MR研究

目的 对原发性高颅压病人的垂体和蝶鞍的形态进行研究。方法 本组包括32例临床诊断为原发性高颅压病人。对垂体和蝶鞍形态进行分级评价。结果 绝大部分原发性高颅压病人（90.6%)出现垂体形态的改变。本组病例中病史短者，垂体和蝶鞍出现形态变化的例数和变化的程度都较病史长者稍轻，但垂体形态的变化（n=29)多于蝶鞍的变化（n=18)。结论 原发性高颅压引起垂体和蝶鞍形态改变，可能与长期高颅压作用于鞍区有关。

The Mechanism and MR Study of Morphological Changes of Pituitary in Idiopathic Intracranial Hypertension

Purpose The Purpose of this study is to demonstrate the morphological changes of pituitary and sella in the patients with idiopathic intracranial hypertension. Methods The MR studies were performed in 32 patients with clinical diagnosis of idiopathic intracanial hypertension (IIH) in this study. Results The morphological changes of pituitary presented more frequently than that of sellar size. The patients with relatively long history tend to have more severe morphological changes in pituitary ( P <0.05) and sella ( P <0.05). Conclusion The long term intracranial hypertension to sellar region may contribute to pituitary and sellar morphological changes.