| NT-proBNP与心肌缺血关系的初步探讨 |
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| 引用本文： | 林茂欢,王景峰,刘香梅,黄至斌,谢双伦,周淑娴,聂如琼. NT-proBNP与心肌缺血关系的初步探讨[J]. 实用全科医学, 2010, 8(2): 165-167 |
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| 作者姓名： | 林茂欢 王景峰 刘香梅 黄至斌 谢双伦 周淑娴 聂如琼 |
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| 作者单位： | 林茂欢,王景峰,黄至斌,谢双伦,周淑娴,聂如琼(中山大学附属第二医院心内科,广东省广州市,510120);刘香梅(中山大学附属第二医院检验科,广东省广州市,510120) |
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| 摘 要： | 目的探讨NT-proBNP与冠心病心肌缺血间的关系。方法用电化学发光方法检测73例冠心病患者入院NT-proBNP浓度,对其中37例行择期PCI的患者再检测术前、术后24小时NT-proBNP浓度。结果冠心病患者血NT-proBNP浓度随着临床分型、冠脉受累支数、冠脉狭窄程度的加重而升高 择期PCI术后血NT-proBNP浓度降低,术前lg（NT-proBNP）为（2.85±0.74）pg/ml,术后lg（NT-proBNP）为（2.64±0.77）pg/ml（P〈0.01）。结论NT-proBNP与冠心病心肌缺血间存在密切的关系,NT-proBNP是冠心病心肌缺血严重程度的一个有效标志物。
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| 关 键 词： | 钠尿肽 心肌缺血 冠状动脉 血管成形术 |
A Preliminary Study on the Relationship between NT-proBNP and Myocardial Ischemia |
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| LIN Mao-huan,WANG Jing-feng,LIU Xiang-mei,et al.. A Preliminary Study on the Relationship between NT-proBNP and Myocardial Ischemia[J]. Applied Journal Of General Practice, 2010, 8(2): 165-167 |
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| Authors: | LIN Mao-huan WANG Jing-feng LIU Xiang-mei et al. |
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| Affiliation: | LIN Mao-huan,WANG Jing-feng,LIU Xiang-mei,et al.Department of Cardiology,the Second Affiliated Hospital of Sun Yat-sen University,Guangzhou 510120,Guangdong,China |
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| Abstract: | Objective To investigate the relationship between NT-proBNP and myocardial ischemia.Methods 73 patients with CHD were enrolled,baseline NT-proBNP levels were assigned by using electrochemiluminescence,and the NT-proBNP levels before and 24 hours after the procedure were also assigned in 37 patients who had undergone elective PCI.Results The concentrations of NT-proBNP correlated with the severity of ischemia,elective PCI reduced the concentrations of NT-proBNP from （2.85±0.74）pg/ml before PCI to （2.64±0.77）pg/ml after the procedure（P0.01）.Conclusion NT-proBNP was closely correlated with myocardial ischemia,it can be served as a effective biomarker of myocardial ischemia. |
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| Keywords: | Natriuretic peptide Myocardial ischemia Coronary artery disease Angioplasty |
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