| 幽门螺杆菌临床分离株耐药性研究 |
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| 引用本文： | 徐平如,吴正林,李俊达,刘芬. 幽门螺杆菌临床分离株耐药性研究[J]. 中华医院感染学杂志, 2003, 13(5): 495-496 |
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| 作者姓名： | 徐平如 吴正林 李俊达 刘芬 |
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| 作者单位： | 深圳市福田区人民医院,广东,深圳,518033 |
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| 摘 要： | 目的 分析深圳地区幽门螺杆菌临床分离株，对多种常用抗幽门螺杆菌抗生素的药敏和耐药情况。方法 采用琼脂稀释法和E-test药敏试验检测幽门螺杆菌对甲硝唑、阿莫西林和克拉霉素的药敏和耐药性。结果 MIC范围：甲硝唑0．54～＞32μg／m1；阿莫西林0．28～＞32μg／m1；克拉霉素＜0．016～1．2μg／m1；耐药情况：65％(E-test法)对甲硝唑耐药，37．5％对阿莫西林耐药，克拉霉素耐药率为0。结论 深圳地区幽门螺杆菌对甲硝唑和阿莫西林耐药率较高，而对克拉霉素无耐药现象。
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| 关 键 词： | 幽门螺杆菌 药敏性 耐药性 |
| 文章编号： | 1005-4529(2003)05-0495-02 |
| 修稿时间： | 2002-11-19 |
Drug Resistance of Clinical Isolates of Helicobacter pylori |
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| XU Ping ru,WU Zhen lin,LI Jun da,LIU Fen. Drug Resistance of Clinical Isolates of Helicobacter pylori[J]. Chinese Journal of Nosocomiology, 2003, 13(5): 495-496 |
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| Authors: | XU Ping ru WU Zhen lin LI Jun da LIU Fen |
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| Abstract: | OBJECTIVE To analyze the antibiotic resistance of Helicobacter pylori (HP) clinical isolates in Shenzhen area. METHODS The susceptibility of HP to metronidazole (MZ), amoxicillin (AM) and clarithromycin (CH) were tested by E test and agar diluted method. RESULTS (1)The range of MIC: MZ 0.54 >32; AM 0.28 >32; CH <0.016 1.2. (2)Resistance: 65% HP was resistant to MZ (E test); 37.5% to AM; the drug resistant rate of CH was zero. CONCLUSIONS HP clinical isolates in Shenzhen are easily resistant to metronidazole and amoxicillin, but susceptible to clarithromycin. |
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