304例重度子痫前期患者终止妊娠时机和妊娠结局分析

目的 分析重度子痈前期的并发症及其妊娠结局,寻求终止妊娠最佳时机和方式.方法 对304例重度子痈前期患者进行回顾性分析,比较不同孕周及分娩方式与母婴顸后的关系.结果 304例重度子痈前期合并肝功能异常、肾功能异常、重度贫血、低蛋白血症、高血压性心脏病、胎盘早剥、HELLP综合征、DIC及产后出血等275例,其发生率为90.5%.不同孕周分娩方式均以剖宫产为主(79.6%),孕<34周组经阴道分娩相对较多,其中有12例为引产;而≥34孕周组剖宫产率较高,但与前者比较差异无统计学意义(P>0.05).新生儿窒息发生率为11.8%(36/304),围产儿死亡率为8.9%(27/304),三组新生儿窒息率和围产儿死亡率比较差异有统计学意义;孕<34周分娩组新生儿窒息率和围生儿死亡率最高(P<0.05).重度子痈前期在37周孕周前终止妊娠者,其胎盘早剥、胎儿宫內窘迫的发生率明显高于≥37孕周终止妊娠者.304例患者经治疗后痊愈出院,无孕产妇死亡.结论 重度子痈前期并发症随着孕周增加而增多,适时终止妊娠可减少母娶并发症,降低围产儿死亡.孕34周以后在促胎肺成熟后择期剖宫产;病情特别严重者,剖宫产分娩时机可提前到孕32周以前甚至剖宫取胚.足月者胎儿宫颈成熟,病情允许的情况下可以经阴道分娩.

Time and method of pregnancy termination in severe preeclampsia and the pregnancy outcome

Objective To study the relationship between the time and method of pregnancy termination and the pregnancy outcome.Methods 304 pregnant women suffered from severe preeclampsia were enrolled for study.The outcome of mothers and new borns including the rates of neonatal asphyxia,perinatal mortality were observed.Results There was no maternal death.The cesarean section rate was 79.6%.Neonatal asphyxia rate was 11.8%,The perinatal mortality rate was 8.9%.Conclusion In severe preeclampsia,pregnancy should be terminated in time,pregnancy terminated is one of the most important treatment methods,and cesarean section is the first choice.