| 宫颈癌术前新辅助化疗的疗效观察 |
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| 引用本文： | 王小芳,何翔. 宫颈癌术前新辅助化疗的疗效观察[J]. 四川医学, 2012, 33(6): 1006-1007 |
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| 作者姓名： | 王小芳 何翔 |
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| 作者单位： | 1. 成都市龙泉驿区第一人民医院妇产科,四川成都,610100
2. 四川大学华西第二医院妇产科,四川成都,610041 |
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| 摘 要： | 目的探讨术前新辅助化疗对巨块型宫颈癌的疗效。方法选择2007年1月～2011年6月我院经病理确诊的14例Ⅰb2～Ⅱa期巨块型宫颈癌,采用BP方案化疗2疗程后手术。结果化疗后临床有效率达83.9%,肿瘤直径较化疗前有不同程度的缩小,差异有统计学意义(P<0.01),所有患者均能顺利切除病灶。结论术前新辅助化疗可提高手术切除率和症状改善率,提高宫颈癌的疗效,为治疗该病的一种有效手段,具有重要的临床意义。
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| 关 键 词： | 新辅助化疗 宫颈癌 手术 |
An observation on curative effect of pre-operation neoadjuvant chemotherapy for cervical cancer |
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| WANG Xiao-fang , HE Xiang. An observation on curative effect of pre-operation neoadjuvant chemotherapy for cervical cancer[J]. Sichuan Medical Journal, 2012, 33(6): 1006-1007 |
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| Authors: | WANG Xiao-fang HE Xiang |
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| Affiliation: | 1.The First People’s Hospital of Longquanyi Distrid,Chengdu,Sichuan 610100;2.West China Second Hospital,Sichuan University,Chengdu,Sichuan 610041,China |
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| Abstract: | Objective To investigate the effect of preoperative neoadjuvant chemotherapy on Ⅰb2~Ⅱa bulky cervical cancer.Methods Totally 14 cases of bulky cervical cancer in stage Ⅰb2~Ⅱa were diagnosed by pathology in our hospital between 2005 and 2009.They were managed by regimen of BP chemotherapy for 2 cycles and followed by operation.Results The overall response rate was 83.9 %.The primary tumor sizeswere significantly decreased after chemotherapy compared with that of before(P<0.01).All patients under went radical hysterect-omy easily.Conclusion Preoperative neoadjuvant chemotherapy could apparently increase the chance of operation and perfect the remission rate.And it is an effective method for treatment of stageⅠb2~Ⅱa bulky cervical cancer.It shows promising prospect in clinical application. |
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| Keywords: | neoadjuvant chemotherapy cervical cancer surgery |
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