| 微重力影响造血干/祖细胞生物学特性及其机制研究进展 |
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| 引用本文： | 刘竞争,郑磊,王前. 微重力影响造血干/祖细胞生物学特性及其机制研究进展[J]. 国际生物医学工程杂志, 2008, 31(4) |
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| 作者姓名： | 刘竞争 郑磊 王前 |
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| 作者单位： | 南方医科大学南方医院医学检验中心,广州,510515;南方医科大学南方医院医学检验中心,广州,510515;南方医科大学南方医院医学检验中心,广州,510515 |
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| 摘 要： | 造血干/祖细胞具有自我更新、增殖及多向分化的功能,从而使机体维持正常的造血.机体在微重力环境下会出现外周血细胞数量和功能的改变,其中有多方面的原因,而在微重力环境下造血干/祖细胞生物学特性的改变是这一改变的主要因素.对微重力如何影响造血干/祖细胞的迁移、增殖及分化等生物学特性进行了综合评述.
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| 关 键 词： | 微重力 造血干 祖细胞 生物学特性 |
Effect and it's mechanism of microgravity on biological characteristics of hematopoietic stem/progenitor cells |
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| LIU Ying-zheng,ZHENG Lei,WANG Qian. Effect and it's mechanism of microgravity on biological characteristics of hematopoietic stem/progenitor cells[J]. International Journal of Biomedical Engineering, 2008, 31(4) |
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| Authors: | LIU Ying-zheng ZHENG Lei WANG Qian |
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| Abstract: | Hematopoietic stem/progenitor cells have the potential of self-renewal,proliferation and multidirectional differentiation,which maintain the normal haematopoiesis of bnmml body.Alterations in the number and function of mature blood cells in the peripheral blood commonly observed in humans exposed to microgravity (μ-g)are results of many reasons.The change of biological characteristic of hematopoietic stem/progenitor cells is one of the important ressons.Migration,proliferation,and differentiation of hematopoietic stem/progenitor cells under microgravity are summarized in this article. |
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| Keywords: | Microgravity Hematopoietic stem/progenitor cell Biological characteristics |
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