首页 | 本学科首页   官方微博 | 高级检索  
检索        


5-HT2 antagonists reduce ON responses in the rabbit retina
Authors:William J Brunken  Nigel W Daw
Abstract:We have investigated the effects of serotonin (5-HT2) antagonists in the rabbit retina. These antagonists reduce the ON responses of ON-center cells as well as the surround (ON) responses of OFF-center cells, and enhance the center (OFF) responses of the latter cells. The result is consistent with the anatomy of the indoleamine-accumulating cells in the rabbit retina, which ramify in sublamina b (ON) of the inner plexiform layer and contact primarily bipolar cells that are depolarizing in the rabbit. This suggests that at least part of the surround (ON) responses to OFF-center cells is generated in the inner plexiform layer.
Keywords:Retina  Serotonin antagonist  Ketanserin  LY-53857  Methysergide  Ganglion cell  Rabbit
本文献已被 ScienceDirect 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号