| 丹参降压颗粒剂的提取工艺研究 |
| |
| 引用本文： | 林以宁,富志军,叶华,亢俊伟.丹参降压颗粒剂的提取工艺研究[J].中国药房,2003,14(2):77-78. |
| |
| 作者姓名： | 林以宁 富志军 叶华 亢俊伟 |
| |
| 作者单位： | 中国药科大学中药制剂教研室,南京市 210038 |
| |
| 摘 要： | 目的 :优选丹参降压颗粒剂的最佳提取工艺。方法 :采用L9(34)正交设计 ,以水溶性酚酸、固形物得率为筛选指标 ,考察浸泡时间、煎煮次数、煎煮时间、加水量4个因素对提取的影响。结果 :最佳提取工艺为药材粉碎过20目筛 ,混匀后用8倍水浸泡1 5h ,煎1 5h ,第2次6倍水煎1 0h。结论 :本工艺经中试试验 ,重现性好。
|
| 关 键 词： | 水溶性酚酸 原儿茶醛 正交试验 提取工艺 |
| 文章编号： | 1001-0408(2003)02-0077-02 |
| 修稿时间： | 2002年1月28日 |
Study on the Extraction Method of Danshen Granules |
| |
| LIN Yining,FU Zhijun,YE Hua,KANG Junwei.Study on the Extraction Method of Danshen Granules[J].China Pharmacy,2003,14(2):77-78. |
| |
| Authors: | LIN Yining FU Zhijun YE Hua KANG Junwei |
| |
| Abstract: | OBJECTIVE:To find the optimal extraction method for Danshen granules METHODS:According to the orthogonal design L9(34),four factors in extraction were optimized,i e soak duration,decocting times,decocting duration and amount of water added The content of salvianolic acid and the weight of solids were taken as indices RESULTS:The best extracting condition was that 20 mesh size of particles was soaked in eight times amount of water for 1 5h,decocted for 1 5h at first,and then six times amount of water for 1 0h CONCLUSION:This technique is highly repeatable in pilot-experiment |
| |
| Keywords: | salvianolic acid protocatechualdehyde orthogonal design extraction method |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
