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生长抑素与肝癌
引用本文:孙政勤,胡和平.生长抑素与肝癌[J].国际消化病杂志,2006,26(2):125-127.
作者姓名:孙政勤  胡和平
作者单位:上海东方肝胆外科医院消化内科,200438
摘    要:生长抑素是一种具有广泛生物学活性的物质,对神经内分泌肿瘤有较强的抑制作用。动物实验和多数临床试验证实生长抑素类似物具有显著抗肿瘤作用,能改善肝癌患者预后及提高生存率。但近几年的临床试验结果却与上述结果有众多矛盾之处,生长抑素类似物的抗肿瘤作用现已受到质疑。此文将对生长抑素类似物在肝癌治疗中的作用作一综述。

关 键 词:生长抑素  奥曲肽  肝脏肿瘤  肝癌
收稿时间:2005-06-28
修稿时间:2005年6月28日

Somatostatin and hepatocellular carcinoma
SUN Zheng-qin,HU He-ping.Somatostatin and hepatocellular carcinoma[J].International Journal of Digestive Disease,2006,26(2):125-127.
Authors:SUN Zheng-qin  HU He-ping
Abstract:Somatostatin is a kind of cytokine having general biologic activity, and has strongly inhibitoy action on neuroendocrine tumor. Many clinical trials and animal experiments confirmed that somatosatin analog has anti-tumor effect obviously and can improve prognosis of HCC and the survival rate. However, there are contradictions between clinical test results, in recent years. Anti-tumor effect of somatoststin analog has been questioned. The role of somatostatin in the therapy of hepatocellular carcinoma will be reviewed in this article.
Keywords:Somatostatin  Octreotidt  Liver tumor  Hepatocellular carcinoma
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