An electron microscopic study of astroglia and oligodendroglia in the lateral geniculate nucleus of aged rats |
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Authors: | C de la Roza J Cano F Reinoso-Suárez |
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Institution: | Department of Morphology, Faculty of Medicine, Autonomous University of Madrid, c/Arzobispo Morcillo 4, Madrid 28029 Spain |
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Abstract: | The ultrastructural features of glial cells in the lateral geniculate nucleus of aged rats have been studied. Abundant filaments as well as heterogeneous dense bodies are observed in the majority of astrocytes. They frequently surround both axons and nerve terminals showing signs of degeneration. In addition, some degenerating myelinated axons are seen in phase suggestive of engulfment by astrocyte processes. Oligodendrocytes display broad processes containing an organelle-rich cytoplasm and a continuity between their plasma membrane and the outer myelin lamellae which partially ensheath the adjacent axons. Multivesicular bodies and pleomorphic dense inclusions, composed of amorphous material as well as laminated structures, are also present in oligodendrocytes. The significance of these morphological features is discussed in relation to process of normal ageing. |
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Keywords: | Lateral geniculate nucleus Astroglia Oligodendroglia Ultrastructure Aged rats |
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