| 康莱特联合化疗药物增敏的最佳时机的实验研究 |
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| 引用本文： | 李瑛,焦顺昌,杨俊兰,孙胜杰,魏秀芳. 康莱特联合化疗药物增敏的最佳时机的实验研究[J]. 现代肿瘤医学, 2006, 14(6): 654-656 |
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| 作者姓名： | 李瑛 焦顺昌 杨俊兰 孙胜杰 魏秀芳 |
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| 作者单位： | 解放军总医院肿瘤科,北京,100853 |
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| 摘 要： | 目的:寻找康莱特联合化疗药物健择和顺铂的最佳时机。方法:采用MTT比色的方法。结果:康莱特对人肺腺癌95D的生长有抑制作用和化疗增敏作用;康莱特先于健择,顺铂加入对95D的抑制最强。结论:康莱特先于健择或顺铂加入优于两药同时加入。
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| 关 键 词： | 康莱特 MTT 肺癌细胞 化疗增敏 |
| 文章编号： | 1672-4992-（2006）06-0654-04 |
| 收稿时间： | 2005-12-15 |
| 修稿时间： | 2005-12-15 |
Experiment of the drug sensitivity of Kanglaite injection on lung cancer cell |
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| LI Ying,JIAO Shun-chang,YANG Jun-lan,SUN Sheng-jie,WEI Xiu-fang. Experiment of the drug sensitivity of Kanglaite injection on lung cancer cell[J]. Journal of Modern Oncology, 2006, 14(6): 654-656 |
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| Authors: | LI Ying JIAO Shun-chang YANG Jun-lan SUN Sheng-jie WEI Xiu-fang |
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| Abstract: | Objective:To investigte the effects of kanglaite(KLT)on drug sensitivity of Gemzar,DDP to 95D cells in vitro,and find the best time of combination. Methods:MTT assay was ased . Ruslts:Various concentration of KLT and Gemzar,DDP could inhibit the proliferation of 95D cells. KLT could advance the sensitivity of Gemzar and DDP to 95D cells(P<0.005).Especially when KLT was used before Gemzar/DDP. Conclusion: KLT could sensitize 95D cells to Gemzar and DDP in vitro. Especially when KLT is used in first. |
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| Keywords: | KLT injection MTT chemosensitization lung cancer cell |
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