| IGF系统与胎儿生长发育 |
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| 引用本文： | 闫震,汤春生.IGF系统与胎儿生长发育[J].中国妇幼健康研究,2004,15(1):17-19. |
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| 作者姓名： | 闫震 汤春生 |
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| 作者单位： | 山东省立医院妇产科,山东,济南,250021;山东省立医院妇产科,山东,济南,250021 |
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| 摘 要： | 胎儿几乎所有组织中都能合成及分泌胰岛素样生长因子。胰岛素样生长因子以自分泌和旁分泌机制与靶细胞表面特异受体结合 ,在局部组织发挥生理作用 ,加强机体同化作用。其对胎儿是必需的 ,在胎儿组织器官生长发育和成熟中起重要作用。母体及胎盘胰岛素样生长因子水平也影响胎儿的生长。基因重组多肽类生长因子已用于产科临床治疗一些相关病症
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| 关 键 词： | 胰岛素样生长因子系统 胎儿生长 胎儿生长受限 |
| 文章编号： | 1008-2514(2004)01-0017-03 |
| 修稿时间： | 2003年10月13 |
IGF system and fetal growth and development |
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| YAN Zhen,TANG Chun-sheng.IGF system and fetal growth and development[J].Chinese Journal of Maternal and Child Health Research,2004,15(1):17-19. |
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| Authors: | YAN Zhen TANG Chun-sheng |
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| Abstract: | Insulin-like growth factors (IGFs) can be synthesized and secreted by almost all fetal organs through autocrine and paracrine ways. It can bind to specific receptors on the cell surface to exert its physiological roles in local tissues and strengthen the assimilation of the body. IGFs are necessary for the fetus and play important roles in growth, development and mature of fetal organs. IGFs in maternal plasma and placenta also affect fetal growth and development. Recombinant human IGF-1(rhIGF-1) has been used to treat some obstetric associated diseases. |
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| Keywords: | insulin-like growth factor system fetal growth fetal growth restriction |
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