| 3种根除幽门螺杆菌治疗方案的临床疗效分析 |
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| 引用本文： | 戴娜,冯堃,陆永高,王炳芳,张丽,包洁,胡渊文. 3种根除幽门螺杆菌治疗方案的临床疗效分析[J]. 实用临床医药杂志, 2011, 15(11): 60-62 |
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| 作者姓名： | 戴娜 冯堃 陆永高 王炳芳 张丽 包洁 胡渊文 |
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| 作者单位： | 江苏省昆山市第一人民医院,消化科,江苏,昆山,215300 |
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| 摘 要： | 目的探讨3种根除幽门螺杆菌(HP)方案的临床疗效及安全性。方法选择经快速尿素酶确诊HP感染的171例患者,随机分为3组,每组选用1种治疗方案进行治疗。其中A组患者给予埃索美拉唑20 mg每日2次+左氧氟沙星0.5 g每日1次+阿莫西林1.0 g每日2次,共7 d;B组患者给予埃索美拉唑20 mg每日2次+阿莫西林1.0 g每日2次(第1～5日);埃索美拉唑20 mg每日2次+克拉霉素0.5 g每日2次+替硝唑0.4 g每日2次(第6～10日);C组:埃索美拉唑20 mg每日2次+阿莫西林1.0 g每日2次(第1～5日);埃索美拉唑20 mg每日2次+左氧氟沙星0.5 g每日1次+替硝唑0.4 g每日2次(第6～10日),疗程结束4周后复查HP。结果 A组根除率为87.3%,B组根除率为92.6%,C组根除率为96.2%。A组与B组、C组根除率比较,差异均有统计学意义(P<0.05),B组与C组根除率比较,差异无统计学意义(P>0.05)。3组不良反应比较差异无统计学意义。结论 3种方案中,B组、C组采用的治疗方案根治率高于A组治疗方案,B组和C组治疗方案在此次试验中差异无统计学意义。
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| 关 键 词： | 幽门螺杆菌 序贯疗法 |
The clinical analysis of the efficacy of three kinds of thiple strategy of Helicobacter pylori (HP) eradication |
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| DAI Na,FENG Kun,LU Yong-gao,WANG Bin-fang,ZHANG Li,BAO Jie,HU Yuan-wen. The clinical analysis of the efficacy of three kinds of thiple strategy of Helicobacter pylori (HP) eradication[J]. Journal of Clinical Medicine in Practice, 2011, 15(11): 60-62 |
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| Authors: | DAI Na FENG Kun LU Yong-gao WANG Bin-fang ZHANG Li BAO Jie HU Yuan-wen |
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| Affiliation: | (Kunshan No.1 People′s Hospital,Kunshan,Jiangsu,215300) |
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| Abstract: | Objective To evaluate the efficacy and safety of three kinds of thiple strategy of Helicobacter pylori(HP) eradication.Methods A total of 171 patients who suffered from HP infection,confirmed by 13C-urea breath test(UBT),were randomly divided into 3 groups,Each group was randomly treated with one of the A,B,C strategy,and named as group A,group B,group C.Group A was treated with Esomeprazole,Levofloxacin,Amoxicillin,group B was treated with Esomeprazole,Amoxicillin(1-5 days),Esomeprazole,Clarithromycin and ... |
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| Keywords: | Hp eradication sequential regimen |
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