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中风急性期腑气不通证候组合及与垂体-肾上腺轴激素关系的研究
引用本文:罗玉韵,关少侠,陈昕,刘东生. 中风急性期腑气不通证候组合及与垂体-肾上腺轴激素关系的研究[J]. 中西医结合心脑血管病杂志, 2011, 9(7)
作者姓名:罗玉韵  关少侠  陈昕  刘东生
作者单位:广东省中医院珠海医院,519015
摘    要:目的 探讨中风急性期腑气不通的症候组合及其与垂体-肾上腺轴激素[促肾上腺皮质激素(ACTH)、皮质醇(CS)]的关系.方法 对278例中风急性期患者进行证候评分,并根据便秘诊断标准分为腑气不通组与非腑气不通组,比较两组间证候组合差别.放射免疫分析(RIA)法测定血中ACTH、CS含量,对比腑气不通组不同证型间ACTH、CS水平,并与非腑气不通组相比较.结果 腑气不通组患者风+火+痰组合所占比例远高于其他组合;非腑气不通组以痰、阴虚、气虚组合为主.ACTH、CS含量水平比较:腑气不通组ACTH、CS比非腑气不通组高(P<0.01); 腑气不通组证候组合间比较,风+火+痰、痰+火组合较其他组合高,以风+火+痰组合升高最为明显,与其他组合比较具有统计学意义(P<0.05或P<0.01).结论 中风腑气不通患者血浆中ACTH、CS升高明显,腑气不通患者血浆中ACTH、CS含量水平与其中医证候组合特点之间存在一定的联系.

关 键 词:急性中风  腑气不通  证候  垂体-肾上腺轴激素

Relationship between the Syndrome Element Combination and Pituitary-adrenal Axis Hormone in Costive Patiens with Acute Stroke
Luo Yuyun,Guan Shaoxia,Chen Xin,et al Zhuhai Branch,Guangdong Hospital of Traditional Chinese Medicine. Relationship between the Syndrome Element Combination and Pituitary-adrenal Axis Hormone in Costive Patiens with Acute Stroke[J]. Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, 2011, 9(7)
Authors:Luo Yuyun  Guan Shaoxia  Chen Xin  et al Zhuhai Branch  Guangdong Hospital of Traditional Chinese Medicine
Affiliation:Luo Yuyun,Guan Shaoxia,Chen Xin,et al Zhuhai Branch,Guangdong Hospital of Traditional Chinese Medicine(Zhuhai 519015)
Abstract:Objective To investigate the relationship between the syndrome element combination and pituitary-adrenal axis hormone in costive patiens with acute stroke.Methods Two hundred and seventy-eight patients in acute stage of stroke were classified according to the syndrome differentiation,and divided into costive group and non-costive group by evaluation tables.The concentrations of plasma adrenocorticotropic hormone(ACTH) and corticosteroid(CS) were detected by radioimmunoassay.Results The main syndrome element...
Keywords:acute stroke  costive  syndrome  pituitary-adrenal axis hormone  
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