米力农治疗重度充血性心力衰竭

目的观察小剂量米力农重度充血性心力衰竭的疗效及安全性。方法心功能Ⅲ、Ⅳ级的重度心衰住院患者60例,随机分为A、B两组,每组各30例。A组为多巴酚丁胺对照组,B组为米力农治疗组。结果 A组显效8例,有效11例,无效11例,总有效率66.7%;B组显效24例,有效4例,无效2例,总有效率93.3%;A组总有效率高于B组,但无显著统计学差异。用超声心动图所测心搏量(SV)、心排血量(CO)、心脏指数(CI),B组各指标明显改善,具有显著统计学差异,而且心律失常发生数减少,未见明显药物不良反应。结论米力农治疗重度充血性心力衰竭安全有效,值得临床广泛应用。

Milrinone treatment of refractory congestive heart failure

Objective To observe the effect and safety with small dose of Milrinone treatment of refractory congestive heart failure.Methods Sixty patients with poor cardiac function grade Ⅲ~Ⅳ hospitalized patients were randomly divided into A,B,30 cases each.Group A represented the Dobutamine group,group B represented Milrinone group.Results As for group A,8 cases were significantly effective,11 cases were effectual and 11 cases were unfruitful with a total cure rate as 66.7%.When it comes to group B,the dates were 24,4,2 respectively,and the total effective rate was 93.3%.The total effective rate was not significantly different between group A and B.Group B were significantly improved in echocardiography stroke volume(SV),cardiac output(CO),cardiac index(CI).There was significant difference in total rate of effects between two groups.There was no significant adverse drug reaction.Conclusion Milrinone treatment of refractory congestive heart failure is safe and effective and is worthy of wider application.