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帕罗西汀治疗幽门螺旋杆菌阴性慢性胃炎临床疗效观察
引用本文:王凤琴. 帕罗西汀治疗幽门螺旋杆菌阴性慢性胃炎临床疗效观察[J]. 实用临床医药杂志, 2011, 15(11)
作者姓名:王凤琴
作者单位:江苏省徐州矿务集团第一医院,消化内科,江苏,徐州,221131
摘    要:目的探讨抗抑郁治疗在幽门螺旋杆菌阴性的慢性胃炎治疗方案中的作用。方法将160例幽门螺旋杆菌阴性的慢性胃炎患者随机分成联合治疗组和常规治疗组(对照组),常规治疗组80例予以奥美拉唑胶囊治疗,联合治疗组80例予以奥美拉唑胶囊及抗抑郁药物(帕罗西汀)联合治疗4周,比较2组治疗前后的疗效。结果联合治疗组后患者的症状改善程度明显优于常规治疗组,生活质量改善,差异有显著性。结论在常规治疗基础上联合抗抑郁药物治疗,对幽门螺旋杆菌阴性的慢性胃炎疗效显著,明显提高生活质量,具有推广意义。

关 键 词:抗抑郁治疗  幽门螺旋杆菌  慢性胃炎

The clinical observation of Paroxetine in the treatment of Helicobacter pylori negative chronic gastritis
WANG Feng-qin. The clinical observation of Paroxetine in the treatment of Helicobacter pylori negative chronic gastritis[J]. Journal of Clinical Medicine in Practice, 2011, 15(11)
Authors:WANG Feng-qin
Affiliation:WANG Feng-qin(The First Hospital of Xuzhou Coal Mining Group,Xuzhou,Jiangsu,221131)
Abstract:Objective To explore the role of antidepressant therapy in H.pylori negative chronic gastritis and treatment programs.Methods One hundred and sixty patients with H.pylori negative chronic gastritis were randomly divided into combined treatment group and the conventional treatment group(control group).Conventional treatment group(n=80) was treated with Omeprazole capsules,while the combined treatment group(n=80) was treated with Omeprazole capsules and antidepressant medication(paroxetine) for 4 weeks.The ef...
Keywords:antidepressant treatment  Helicobacter pylori  chronic gastritis  
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