| 2型糖尿病患者骨密度相关因素分析 |
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| 引用本文： | 张洁,沈默宇,成金罗.2型糖尿病患者骨密度相关因素分析[J].实用临床医药杂志,2011,15(13):32-34,38. |
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| 作者姓名： | 张洁 沈默宇 成金罗 |
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| 作者单位： | 南京医科大学附属常州市第二人民医院,内分泌科,江苏,常州,213001 |
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| 摘 要： | 目的探讨2型糖尿病患者骨密度(BMD)与体重、病程、胰岛功能等因素的相关性。方法 42例2型糖尿病患者(DM)中21例为骨质疏松患者(DM-OP),21例为非骨质疏松患者(DM-NOP),采用双能X线骨密度测定仪测定42例DM患者以及42名正常对照者(NC)正位腰椎(L1~L4)及左侧股骨BMD,并记录两组患者性别、年龄、病程、身高、体重、体质指数、空腹及餐后2 h血糖和胰岛素(Ins)、C肽(CP)、糖化血红蛋白(HbAlc)等临床指标进行比较。结果 DM-OP组患者空腹血清C肽低于DM-NOP组;2型糖尿病患者腰椎BMD与血清C肽水平和体重呈正相关(r=0.318、P=0.040和r=0.457、P=0.002),与糖尿病病程呈负相关(r=-0.312、P=0.044)。DM-OP组BMD较正常对照组明显下降(P<0.05)。结论 2型糖尿病患者骨密度降低与年龄、性别、体重减轻、病程延长、胰岛功能下降等因素有关。
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| 关 键 词： | 2型糖尿病 骨质疏松 骨密度 胰岛素 C肽 |
Analysis of associated factors on bone mineral density of patients with type 2 diabetes |
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| ZHANG Jie,SHEN Mo-yu,CHENG Jin-luo.Analysis of associated factors on bone mineral density of patients with type 2 diabetes[J].Journal of Clinical Medicine in Practice,2011,15(13):32-34,38. |
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| Authors: | ZHANG Jie SHEN Mo-yu CHENG Jin-luo |
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| Institution: | (Changzhou No.2 People′s Hospital,Changzhou,Jiangsu,213001) |
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| Abstract: | Objective To investigate the association between the bone mineral density(BMD) and the factors in patients with type 2 diabetes(T2DM).Methods Forty-two patients with T2DM were equally divided into Osteoporosis group(DM-OP) and non-Osteoporosis group(DM-NOP),and control group(n=42) was enrolled.Lumbar(L1-L4) and left femur Bone-mineral density(BMD) were assessed by dual-energy X ray absorptiomertry.Gender,age,course,height,weight,BMI,blood glucose,insulin,C peptide,HbAlc were also measured.Results Compared w... |
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| Keywords: | diabetes type 2 osteoporosis bone mineral density insulin C peptide |
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