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28例低血糖脑病的病因、临床和神经影像学特点分析
引用本文:张展,范层层,任俊伟,陈娜,杨琴.28例低血糖脑病的病因、临床和神经影像学特点分析[J].重庆医学,2011,40(30):3056-3057,3060.
作者姓名:张展  范层层  任俊伟  陈娜  杨琴
作者单位:1. 重庆市医药卫生学校,408000
2. 重庆医科大学附属第一医院神经内科,400016
摘    要:目的探讨低血糖脑病的病因、临床和神经影像学特点。方法回顾性分析28例低血糖脑病患者的病因、临床和神经影像学资料。结果本组患者13例有明确糖尿病史,均行降糖药物治疗;8例患者疑糖尿病而服降糖药物,胰岛素瘤4例,原因不明3例。临床表现为意识障碍14例,言语不清、反应迟钝5例,偏瘫和单侧肢体瘫痪3例,精神行为异常3例,痫性发作3例。8例头颅CT或MRI未见明显异常;7例头颅CT示双侧基底节区对称性低密度灶,20例MRI检查异常,主要累及双侧基底节区、大脑皮质、皮质下白质、海马、胼胝体压部和脑干,表现为等或稍长T1、长T2异常信号,Flair像呈高信号,弥散加权成像(DWI)呈高信号。结论低血糖脑病的病因主要是过量使用降糖药物和胰岛素瘤,其临床表现复杂多样,动态监测血糖意义重大,MRI有高度特异性,DWI序列对病变更敏感。

关 键 词:低血糖脑病  磁共振成像  病因

Etiological, clinical and neuroimaging features of hypoglycemic encephalopathy
Zhang Zhan,Fan Cengceng,Ren Junwei,Chen Na,Yang Qin.Etiological, clinical and neuroimaging features of hypoglycemic encephalopathy[J].Chongqing Medical Journal,2011,40(30):3056-3057,3060.
Authors:Zhang Zhan  Fan Cengceng  Ren Junwei  Chen Na  Yang Qin
Institution:Zhang Zhan1,Fan Cengceng2,Ren Junwei2,Chen Na2,Yang Qin2(1.Chongqing Medical and Health Schools,Chongqing 408000,China,2.Department of Neurology,the First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China)
Abstract:Objective To investigate the etiological,clinical and neuroimaging features of hypoglycemic encephalopathy(HE).Methods 28 hypoglycemic encephalopathy patients were analyzed including the etiological,clinical and neuroimaging data retrospectively.Results Among all the HE cases,there was 13 cases of diabetes mellitus,which were treated by hypoglycemic agents,8 cases of possibly diabetes mellitus,which were administrated with oral hypoglycemic agents and 4 cases of insulinoma with unclear reason.There were 14 ...
Keywords:hypoglycemia  magnetic resonance imaging  etiological factor  
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