| 扶正化瘀胶囊抗肝纤维化的临床疗效和作用机制 |
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| 引用本文： | 赵长青,吴艺青,徐列明.扶正化瘀胶囊抗肝纤维化的临床疗效和作用机制[J].中西医结合学报,2006,4(5):467-472. |
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| 作者姓名： | 赵长青 吴艺青 徐列明 |
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| 作者单位： | 1. 上海中医药大学肝病研究所,上海,201203;上海中医药大学曙光医院肝硬化科,上海,201203
2. 上海中医药大学肝病研究所,上海,201203 |
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| 摘 要： | 正虚血瘀是肝纤维化的基本病机,扶正化瘀胶囊是针对此基本病机制成的抗肝纤维化药物。十多年来的临床和实验研究发现,该药可通过保护肝细胞、减轻肝损伤、抑制肝纤维化的形成等多种作用机制,来发挥其在抗肝纤维化、逆转肝纤维化、改善肝功能等方面的临床疗效。扶正化瘀胶囊是一个作用机制明确,值得临床大力推广的安全有效的抗肝纤维化药物。
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| 关 键 词： | 扶正化瘀胶囊 肝纤维化 临床研究 作用机制 |
| 文章编号： | 1672-1977（2006）05-0467-06 |
| 收稿时间： | 2006-02-27 |
| 修稿时间： | 2006年2月27日 |
Curative effects of Fuzheng Huayu Capsules on hepatic fibrosis and the functional mechanisms: a review |
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| Chang-Qing ZHAO,Yi-Qing WU,Lie-Ming XU.Curative effects of Fuzheng Huayu Capsules on hepatic fibrosis and the functional mechanisms: a review[J].Journal of Chinese Integrative Medicine,2006,4(5):467-472. |
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| Authors: | Chang-Qing ZHAO Yi-Qing WU Lie-Ming XU |
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| Institution: | 1. Institute of Liver Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; 2. Department of Liver Cirrhosis, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China |
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| Abstract: | Deficiency of Qi (healthy energy) and blood stasis are the basic pathological changes of hepatic fibrosis according to the theories of traditional Chinese medicine. Fuzheng Huayu Capsule, a compound Chinese herbal medicine for hepatic fibrosis, is produced in the light of this pathological mechanism. More than a decade of clinical studies and experimental researches show that this medicine has effects of protecting hepatic cells, relieving liver injury, and controlling the development of hepatic fibrosis. It has definite functional mechanisms on anti-hepatic fibrosis. It is a safe and effective medicine for hepatic fibrosis, and deserves to be well introduced to clinic. |
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| Keywords: | Fuzheng Huayu Capsules hepatic fibrosis clinical studies functional mechanisms |
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