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人腺病毒分子生物学分型检测方法的研究进展
引用本文:王瑞欢,陈丽丽,马学军,张红.人腺病毒分子生物学分型检测方法的研究进展[J].实用预防医学,2021,28(3):382-385.
作者姓名:王瑞欢  陈丽丽  马学军  张红
作者单位:1.湖南省疾病预防控制中心, 湖南 长沙 410005;
2.南华大学公共卫生学院, 湖南 衡阳 421001;
3.中国疾病预防控制中心病毒病预防控制所,国家卫生健康委员会医学病毒和病毒病重点实验室,北京 102206
基金项目:十三五重大项目(2018ZX10711001,2017ZX10104001和2018ZX10713-002);湖南省重点研发计划(2017SK2101)。
摘    要:人腺病毒(human adenovirus,HAdV)是引起呼吸道感染的常见病原体,不同型别的组织嗜性不同,由其感染所引起疾病的严重程度也不同。该病毒的感染所致疾病仅靠临床表现很难确定病毒的类型,因此,HAdV的分型鉴定对其所引起疾病的诊断与治疗具有较大的帮助,本文综述了用于该病毒分型检测的分子生物学手段,具有一定的临床意义。

关 键 词:人腺病毒  分子生物学  分型  
收稿时间:2020-08-21

Research progress on molecular biological techniques for human adenovirus detection
WANG Rui-huan,CHEN Li-li,MA Xue-jun,ZHANG Hong.Research progress on molecular biological techniques for human adenovirus detection[J].Practical Preventive Medicine,2021,28(3):382-385.
Authors:WANG Rui-huan  CHEN Li-li  MA Xue-jun  ZHANG Hong
Institution:1. Hunan Provincial Center for Disease Control and Prevention, Changsha, Hunan 410005, China;
2. School of Public Health, University of South China, Hengyang, Hunan 421001, China;
3. NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Abstract:Human adenovirus(HAdV)is the main pathogen causing respiratory infections.Different serotypes have different tissue tropisms,and the severity of the disease caused by them is also different.It is difficult to determine the serotype of HAdV based only on the clinical manifestations of the disease caused by the virus;and hence,serotyping of HAdV is of great help to diagnosis and treatment of the disease.This paper summarizes the molecular biological detection technique and serotyping methods of HAdV,which have certain clinical significance.
Keywords:human adenovirus  molecular biology  serotype
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