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CT and MRI in severe hypophosphataemia with central nervous system involvement
Authors:U Weber  T Hüppe  L Niehaus
Institution:(1) Department of Radiology, Krankenhaus Am Urban, Dieffenbachstrasse 1, 10967 Berlin, Germany, DE;(2) Department of Neuroradiology, University Hospital Charité, Schumannstrasse 20–21, 10098 Berlin, Germany, DE
Abstract:We report a 38-year-old woman with extreme hypophosphataemia in whom CT and MRI disclosed bilateral lesions within the basal ganglia, thalamus and occipital lobes. After adequate substitution of phosphate the lesions grossly resolved and the patient recovered. This case is the first to demonstrate that profound changes of serum phosphate may be associated with reversible brain lesions. Received: 27 March 1999/Accepted: 16 June 1999
Keywords:Hypophosphataemia  Brain  Myelinolysis  extrapontine  Computed tomography  Magnetic resonance imaging
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