甲状腺滤泡性肿瘤Logistic判别分析及预后分析

本文对８５例滤泡性腺癌（ＦＣ）、６１例滤泡性腺瘤及２３例未定性滤泡性肿瘤的临床病理指标进行了多元分析。选出１２项良恶鉴别的指标，建立了ｌｏｇｉｓｔｉｃ判别方程，判别符合率１００％。１４１例获随访结果，其中１１６例随访达１０年以上。随防结果分析显示ＦＣ微小浸润型和明显浸润型自下而上率差异显著，１１项临床病理指标对ＦＣ有预后意义。

LOGISTIC DISCRIMINANT ANALYSIS AND PROGNOSTIC ANALYSIS OF THYROID FOLLICULAR TUMORS.

cases of follicular thyroid tumors including 85 follicular carcinomas (FC), 61 follicular adenomas (FA)and 23 undeterminated follicular tumors (UFT) were investigated. Stepwise regression analysis was applied to find out the main indexes in differentiation between FC and FA, Twelve pathological indexes were selected out to establish the logistic discriminant equation which was used in judgement of FC and FA. The consistent rate was 100%. This equation was proved to be of practical value in the diagnosis of follicular thyroid tumors. The follow-up information was obtained in 141 cases(83. 4%) in which 116 cases (82%) were followed up for more than 10 years. The rates of local recurrence of FC, FA and UFT were not statistically different. but the rates of metastasis and mortality, which only occured in FC,were statistically different, The survival rates was strikingly different between the two types of FC, the minimally invasive carcinoma (MIC) and the widely invasive one (WIC).The 10 year survival rate of MIC was 97.3%, but 60.8% in WIC. Eleven clinico-pathological indexes possessing significant relationship with the prognosis of FC have been demonstrated.